Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013882 | 1.00 | ATM (0.59) | ATMLMNASMN1; SMN2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL28061112 | 0.98 | LMNA (0.59) | ATMLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL11251326 | 0.94 | ATM (0.57) | ATMLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL30356595 | 0.92 | HCAR2 (0.65) | ATMLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL17695736 | 0.92 | LMNA (0.55) | ATMLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8016512 | 0.92 | LMNA (0.55) | ATMLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL544702 | 0.92 | ATM (0.55) | ATMLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL543769 | 0.92 | ATM (0.55) | ATMLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL543771 | 0.92 | ATM (0.55) | ATMLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8489525 | 0.91 | LMNA (0.50) | ATMLMNASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638118-B2 | Aminoalkyl substituted esters and amides of fumaric acid for neutralizing malodor | GIVAUDAN SA (CH) | 2009-12-29 | — | — | US | disclosed |
| EP-1735267-B1 | AMINOALKYL SUBSTITUTED ESTERS AND AMIDES OF FUMARIC ACID FOR NEUTRALISING MALODOR | GIVAUDAN SA (CH) | 2008-07-23 | — | — | EP | disclosed |
| US-20070009475-A1 | Aminoalkyl substituted esters and amides of fumaric acid for neutralizing malodor | GIVAUDAN SA (CH) | 2007-01-11 | — | — | US | disclosed |
| EP-1735267-A1 | AMINOALKYL SUBSTITUTED ESTERS AND AMIDES OF FUMARIC ACID FOR NEUTRALISING MALODOR | Givaudan SA (CH) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005021051-A1 | AMINOALKYL SUBSTITUTED ESTERS AND AMIDES OF FUMARIC ACID FOR NEUTRALISING MALODOR | GIVAUDAN SA (CH) | 2005-03-10 | — | — | WO | disclosed |