Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL543771 | 1.00 | ATM (0.55) | ATMHCAR2ALDH1A1KDM4ELMNA | |
| SCHEMBL543769 | 1.00 | ATM (0.55) | ATMHCAR2ALDH1A1KDM4ELMNA | |
| SCHEMBL11251326 | 0.98 | ATM (0.57) | ATMHCAR2ALDH1A1KDM4ELMNA | |
| SCHEMBL17695740 | 0.93 | ALDH1A1 (0.50) | ATMHCAR2ALDH1A1KDM4ELMNA | |
| SCHEMBL9984524 | 0.93 | HCAR2 (0.67) | ATMHCAR2ALDH1A1KDM4ELMNA | |
| SCHEMBL9984098 | 0.93 | HCAR2 (0.67) | ATMHCAR2ALDH1A1KDM4ELMNA | |
| SCHEMBL17695739 | 0.93 | ALDH1A1 (0.50) | ATMHCAR2ALDH1A1KDM4ELMNA | |
| SCHEMBL9984104 | 0.93 | HCAR2 (0.67) | ATMHCAR2ALDH1A1KDM4ELMNA | |
| SCHEMBL4411164 | 0.92 | ATM (0.59) | ATMHCAR2ALDH1A1KDM4ELMNA | |
| SCHEMBL5013882 | 0.92 | ATM (0.59) | ATMHCAR2ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110625-B2 | Rubber composition | BRIDGESTONE CORPORATION (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20100298488-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
| US-7799856-B2 | Rubber composition | BRIDGESTONE CORPORATION (JP) | 2010-09-21 | — | — | US | disclosed |
| EP-2226354-A1 | Rubber composition | Bridgestone Corporation (JP) | 2010-09-08 | — | — | EP | disclosed |
| EP-2223958-A1 | Rubber composition | Bridgestone Corporation (JP) | 2010-09-01 | — | — | EP | disclosed |
| EP-1435375-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2004-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298488-A1 | RUBBER COMPOSITION | RAD50, RAD54L, VCL | ATM 197/4885HCAR2 2134/4885ALDH1A1 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.