Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 16/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4406000 | 0.87 | FAAH (0.44) | FAAHCNR1CNR2 | |
| SCHEMBL4082474 | 0.86 | FAAH (0.49) | FAAHCNR1CNR2 | |
| SCHEMBL4084842 | 0.85 | FAAH (0.53) | FAAHCNR1CNR2 | |
| SCHEMBL4075866 | 0.85 | FAAH (0.53) | FAAHCNR1CNR2 | |
| SCHEMBL4082480 | 0.85 | FAAH (0.48) | FAAHCNR1CNR2 | |
| SCHEMBL4075585 | 0.84 | GRIN2B (0.56) | FAAHCNR1CNR2 | |
| SCHEMBL4078365 | 0.83 | FAAH (0.51) | FAAHCNR1CNR2 | |
| SCHEMBL5818620 | 0.83 | FAAH (0.50) | FAAHCNR1CNR2 | |
| SCHEMBL4083275 | 0.82 | FAAH (0.52) | FAAHCNR1CNR2 | |
| SCHEMBL4079582 | 0.82 | FAAH (0.45) | FAAHCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620395-B1 | AZETIDINECARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CB1 RECEPTOR MEDIATED DISORDERS | VERNALIS RES LTD (GB) | 2009-12-30 | — | — | EP | claimed |