SCHEMBL4082474

SCHEMBL4082474

CCC(NC(=O)N1CC(OC(c2ccc(Cl)cc2)c2ccccc2Cl)C1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FAAH O00519 15/20 0.49
CNR1 P21554 2/20 0.48
CNR2 P34972 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4075866 0.88 FAAH (0.53) FAAHCNR1CNR2
SCHEMBL4084842 0.88 FAAH (0.53) FAAHCNR1CNR2
SCHEMBL4075585 0.87 GRIN2B (0.56) FAAHCNR1CNR2
SCHEMBL4411218 0.86 FAAH (0.49) FAAHCNR1CNR2
SCHEMBL4078365 0.84 FAAH (0.51) FAAHCNR1CNR2
SCHEMBL4083275 0.83 FAAH (0.52) FAAHCNR1CNR2
SCHEMBL4406000 0.82 FAAH (0.44) FAAHCNR1CNR2
SCHEMBL4082480 0.82 FAAH (0.48) FAAHCNR1CNR2
SCHEMBL4089351 0.82 FAAH (0.50) FAAHCNR1CNR2
SCHEMBL5818620 0.82 FAAH (0.50) FAAHCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620395-B1 AZETIDINECARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CB1 RECEPTOR MEDIATED DISORDERS VERNALIS RES LTD (GB) 2009-12-30 EP claimed
US-7504522-B2 Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders VERNALIS RESEARCH LIMITED (GB) 2009-03-17 US claimed
US-20070054891-A1 Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders VERNALIS RESEARCH LIMAITED (GB) 2007-03-08 US claimed
US-20240000748-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE ANEBULO PHARMACEUTICALS, INC. 2024-01-04 US disclosed
WO-2022109043-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE ANEBULO PHARMACEUTICALS, INC. (US) 2022-05-27 WO disclosed
US-20220151990-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE ANEBULO PHARMACEUTICALS, INC. 2022-05-19 US disclosed
US-20220151990-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE ANEBULO PHARMACEUTICALS, INC. 2022-05-19 US disclosed
US-11141404-B1 Formulations and methods for treating acute cannabinoid overdose ANEBULO PHARMACEUTICALS, INC. (US) 2021-10-12 US disclosed
US-11141404-B1 Formulations and methods for treating acute cannabinoid overdose ANEBULO PHARMACEUTICALS, INC. (US) 2021-10-12 US disclosed
EP-1620395-B1 AZETIDINECARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CB1 RECEPTOR MEDIATED DISORDERS VERNALIS RES LTD (GB) 2009-12-30 EP disclosed
US-7504522-B2 Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders VERNALIS RESEARCH LIMITED (GB) 2009-03-17 US disclosed
US-20070054891-A1 Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders VERNALIS RESEARCH LIMAITED (GB) 2007-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070054891-A1 Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders CNR1, CNR2, GPR119 FAAH 8/4885CNR1 1/4885CNR2 2/4885
US-20240000748-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE CNR1, CNR2, FAAH FAAH 3/4885CNR1 1/4885CNR2 2/4885
US-20220151990-A1 FORMULATIONS AND METHODS FOR TREATING ACUTE CANNABINOID OVERDOSE CNR1, CNR2, FAAH FAAH 3/4885CNR1 1/4885CNR2 2/4885
US-11141404-B1 Formulations and methods for treating acute cannabinoid overdose CNR1, CNR2, FAAH FAAH 3/4885CNR1 1/4885CNR2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.