SCHEMBL4411258

SCHEMBL4411258

CCOc1ccc(CCC(=O)NN)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
SLC5A1 P13866 1/20 0.54
SLC5A2 P31639 1/20 0.54
ACACB O00763 2/20 0.52
POLB P06746 2/20 0.50
LMNA P02545 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALDH1A1 P00352 3/20 0.49
PARP10 Q53GL7 1/20 0.49
FFAR1 O14842 1/20 0.47
FFAR4 Q5NUL3 1/20 0.47
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MEN1 O00255 1/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3862543 0.85 KMT2A (0.49) POLBLMNAL3MBTL1ALDH1A1KMT2A
SCHEMBL3864591 0.84 KMT2A (0.51) POLBLMNAL3MBTL1ALDH1A1KMT2A
SCHEMBL6538553 0.84 S1PR4 (0.57) MAPTLMNAL3MBTL1SMN1; SMN2
SCHEMBL3862402 0.84 GAA (0.48) POLBLMNAL3MBTL1ALDH1A1KMT2A
SCHEMBL13903016 0.83 ALDH1A1 (0.67) MAPTPOLBL3MBTL1ALDH1A1KMT2A
SCHEMBL4409663 0.83 FFAR1 (0.56) POLBLMNAALDH1A1FFAR1FFAR4
SCHEMBL3861180 0.82 ALDH1A1 (0.51) MAPTPOLBLMNAL3MBTL1ALDH1A1
SCHEMBL22282965 0.81 PARP10 (0.58) NPC1SLC5A1SLC5A2ACACBLMNA
SCHEMBL10138384 0.81 PLK1 (0.51) MAPTSLC5A1SLC5A2ACACBPOLB
SCHEMBL12548774 0.80 HTT (0.60) MAPTNPC1RAB9ASLC5A1SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed