Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3862543 | 0.85 | KMT2A (0.49) | KMT2AGAAMEN1POLBCYP2C19 | |
| SCHEMBL3861180 | 0.85 | ALDH1A1 (0.51) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL4411258 | 0.84 | MAPT (0.54) | KMT2AGAAMEN1POLBALDH1A1 | |
| SCHEMBL3862402 | 0.84 | GAA (0.48) | KMT2AGAAMEN1POLBCYP2C19 | |
| SCHEMBL8402471 | 0.81 | ADRB2 (0.56) | KMT2AGAAMEN1ALDH1A1LMNA | |
| SCHEMBL13903016 | 0.81 | ALDH1A1 (0.67) | KMT2AMEN1POLBALDH1A1L3MBTL1 | |
| SCHEMBL4409663 | 0.80 | FFAR1 (0.56) | GAAPOLBCYP2C19ALDH1A1LMNA | |
| SCHEMBL2185554 | 0.79 | TAAR1 (0.53) | — | |
| SCHEMBL6538553 | 0.78 | S1PR4 (0.57) | LMNAL3MBTL1 | |
| SCHEMBL8402106 | 0.77 | PPARA (0.51) | ALDH1A1LMNAL3MBTL1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253166-A1 | Conjugation of Peptides | NOVO NORDISK A/S (DK) | 2009-10-08 | — | — | US | claimed |
| US-20070111926-A1 | Conjugation of peptides | NOVO NORDISK A/S (DK) | 2007-05-17 | — | — | US | claimed |
| EP-1673464-A2 | CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2006-06-28 | — | — | EP | claimed |
| WO-2005035553-A2 | CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2005-04-21 | — | — | WO | claimed |
| US-20090253166-A1 | Conjugation of Peptides | NOVO NORDISK A/S (DK) | 2009-10-08 | — | — | US | disclosed |
| US-20090176967-A1 | Conjugation of FVII | NOVO NORDISK HEALTHCARE A/G (CH) | 2009-07-09 | — | — | US | disclosed |
| US-7524813-B2 | Selectively conjugated peptides and methods of making the same | NOVO NORDISK HEALTH CARE AG (CH) | 2009-04-28 | — | — | US | disclosed |
| US-20070111926-A1 | Conjugation of peptides | NOVO NORDISK A/S (DK) | 2007-05-17 | — | — | US | disclosed |
| EP-1778838-A2 | CONJUGATION OF FVII | Novo Nordisk Health Care AG (CH) | 2007-05-02 | — | — | EP | disclosed |
| EP-1673464-A2 | CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2006-06-28 | — | — | EP | disclosed |
| WO-2006013202-A2 | CONJUGATION OF FVII | NOVO NORDISK HEALTH CARE AG (DK) | 2006-02-09 | — | — | WO | disclosed |
| WO-2005035553-A2 | CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2005-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176967-A1 | Conjugation of FVII | F13B, F13A1, FGB | KMT2A 3202/4885GAA 3379/4885MEN1 2945/4885 |
| US-20070111926-A1 | Conjugation of peptides | DNPEP, ENPEP, ANPEP | KMT2A 2475/4885GAA 426/4885MEN1 1266/4885 |
| US-20090253166-A1 | Conjugation of Peptides | DNPEP, ENPEP, ANPEP | KMT2A 2475/4885GAA 426/4885MEN1 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.