SCHEMBL4411289

SCHEMBL4411289

CC(=O)Nc1cccc(C(=N)NO)c1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.57
RAB9A P51151 4/20 0.57
LMNA P02545 3/20 0.57
TP53 P04637 3/20 0.57
NPC1 O15118 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
ATM Q13315 3/20 0.55
NTSR1 P30989 1/20 0.55
ALDH1A1 P00352 4/20 0.54
CYP1A2 P05177 1/20 0.54
HSD17B10 Q99714 1/20 0.54
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
RECQL P46063 1/20 0.51
POLB P06746 1/20 0.50
NR4A1 P22736 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6324587 0.85 KCNK3 (0.49) MAPTRAB9ATP53NPC1SMN1; SMN2
SCHEMBL4401147 0.83 HDAC6 (0.62) MAPTRAB9ALMNATP53NPC1
SCHEMBL474709 0.82 KMT2A (0.70) MAPTRAB9ALMNATP53NPC1
SCHEMBL1436168 0.81 ALDH1A1 (0.59) MAPTRAB9ALMNATP53NPC1
SCHEMBL7041993 0.81 ALDH1A1 (0.59) MAPTRAB9ALMNATP53NPC1
Hydrochloric Acid SCHEMBL3576551 0.80 ALDH1A1 (0.57) MAPTRAB9ALMNATP53NPC1
SCHEMBL4503350 0.79 HDAC3 (0.60) RAB9ALMNACYP1A2
SCHEMBL31022695 0.79 MEN1 (0.62) MAPTRAB9ALMNATP53NPC1
SCHEMBL758991 0.79 MEN1 (0.62) MAPTRAB9ALMNATP53NPC1
SCHEMBL7903322 0.79 SMN1; SMN2 (0.55) MAPTRAB9ATP53NPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 WO disclosed
EP-1959951-B1 HETEROARYL SUBSTITUTED PIPERIDINE DERIVATIVES AS L-CPT1 INHIBITORS HOFFMANN LA ROCHE (CH) 2009-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MAPT 2999/4885RAB9A 2370/4885LMNA 1344/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MAPT 2999/4885RAB9A 2370/4885LMNA 1344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.