SCHEMBL758991

SCHEMBL758991

CC(=O)Nc1cccc(C(=O)O)c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
HSD17B10 Q99714 2/20 0.61
ALDH1A1 P00352 2/20 0.61
CYP1A2 P05177 1/20 0.61
NAPRT Q6XQN6 1/20 0.61
RAB9A P51151 4/20 0.60
NPC1 O15118 3/20 0.60
MITF O75030 1/20 0.59
LMNA P02545 1/20 0.59
TP53 P04637 1/20 0.59
MAPT P10636 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
HPSE Q9Y251 1/20 0.58
CBS P35520 1/20 0.57
AKR1B10 O60218 1/20 0.56
AKR1B1 P15121 1/20 0.56
AKR1C4 P17516 1/20 0.56
AKR1C3 P42330 1/20 0.56
AKR1C2 P52895 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31022695 1.00 MEN1 (0.62) MEN1KMT2AHSD17B10ALDH1A1CYP1A2
SCHEMBL7778741 0.98 MEN1 (0.60) MEN1KMT2AHSD17B10ALDH1A1CYP1A2
Acetic Acid SCHEMBL6444184 0.98 MEN1 (0.60) MEN1KMT2AHSD17B10ALDH1A1CYP1A2
SCHEMBL474709 0.88 KMT2A (0.70) MEN1KMT2AHSD17B10ALDH1A1CYP1A2
SCHEMBL11031257 0.85 ALDH1A1 (0.71) MEN1KMT2AHSD17B10ALDH1A1CYP1A2
SCHEMBL23932088 0.84 KMT2A (0.66) MEN1KMT2AALDH1A1RAB9ANPC1
SCHEMBL4749812 0.84 NPC1 (0.80) MEN1KMT2ARAB9ANPC1MITF
SCHEMBL1901172 0.83 ALDH1A1 (0.76) MEN1KMT2AHSD17B10ALDH1A1CYP1A2
SCHEMBL895009 0.83 PARP1 (0.63) MEN1KMT2AHSD17B10ALDH1A1CYP1A2
SCHEMBL2328579 0.83 ALDH1A1 (0.59) MEN1KMT2AHSD17B10ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250376444-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES CYTOKINETICS INC (US) 2025-12-11 US claimed
CN-115915796-A Multifunctional Lewis base molecule modified high-stability perovskite solar cell 河北工业大学 2023-04-04 CN claimed
CN-115611814-A Compound containing 2-aminoimidazole ring and preparation method and application thereof 烟台新药创制山东省实验室 2023-01-17 CN claimed
US-20220298114-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES CYTOKINETICS, INC. 2022-09-22 US claimed
EP-3821882-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES Amgen Inc. (US) 2021-05-19 EP claimed
CN-111548562-A Preparation method of composite polypropylene plastic 马健珂 2020-08-18 CN claimed
EP-2644639-B1 METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN AND METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN COMPOUND SHENZHEN WOTE ADVANCED MAT CO LTD (CN) 2017-09-20 EP claimed
CN-103328540-B Method for preparing wholly aromatic liquid crystalline polyester amide resin and method for preparing wholly aromatic liquid crystalline polyester amide resin compound SHENZHEN WOTE ADVANCED MATERIALS CO LTD 2015-04-29 CN claimed
US-20140309235-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES CYTOKINETICS, INC. (US) 2014-10-16 US claimed
US-8859711-B2 Method for preparing wholly aromatic liquid crystalline polyester amide resin and method for preparing wholly aromatic liquid crystalline polyester amide resin compound SAMSUNG FINE CHEMICALS CO., LTD. (KR) 2014-10-14 US claimed
EP-2644639-A2 METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN AND METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN COMPOUND Samsung Fine Chemicals Co., Ltd. (KR) 2013-10-02 EP claimed
CN-103328540-A Method for preparing wholly aromatic liquid crystalline polyester amide resin and method for preparing wholly aromatic liquid crystalline polyester amide resin compound SAMSUNG FINE CHEMICALS CO LTD 2013-09-25 CN claimed
US-20130231453-A1 METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN AND METHOD FOR PREPARING WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER AMIDE RESIN COMPOUND SAMSUNG FINE CHEMICALS CO., LTD. (KR) 2013-09-05 US claimed
CN-102702006-A Preparation method of 3-amino-2-ethyl nitrobenzoate SHENGSHI TAIKE BIOMEDICAL TECHNOLOGY SUZHOU CO LTD 2012-10-03 CN claimed
EP-0534817-B1 Esterification process of salts of carboxylic acids RHODIA CHIMIE SA (FR) 1998-12-09 EP claimed
EP-0539274-B1 Method for the synthesis of aldehydes and of their derivatives RHONE POULENC CHIMIE (FR) 1996-04-10 EP claimed
EP-4456200-B1 SECONDARY BATTERY POSITIVE ELECTRODE, PRODUCTION METHOD THEREFOR, AND SECONDARY BATTERY PANASONIC IP MAN CO LTD (JP) 2026-05-06 EP disclosed
US-12612366-B2 Salts and crystal forms of omecamtiv mecarbil AMGEN INC. (US) 2026-04-28 US disclosed
US-4254208-A DISPERSION, LIQUEFYING, SOLIDS FUJI PHOTO FILM CO., LTD. (JP) 1981-03-03 US disclosed
US-4239815-A BY COATING A SUPPORT WITH A POLYVALENT METAL SALT AND THEN A COATING OF AN AROMATIC CARBOXYLIC ACID SALT FUJI PHOTO FILM CO., LTD. (JP) 1980-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140309235-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES SI, MLN, MLNR MEN1 295/4885KMT2A 1454/4885HSD17B10 3993/4885
US-12612366-B2 Salts and crystal forms of omecamtiv mecarbil SLC28A1, SLC28A2, SLC34A1 MEN1 1254/4885KMT2A 1272/4885HSD17B10 4319/4885
US-20250376444-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES SI, MLN, MLNR MEN1 295/4885KMT2A 1454/4885HSD17B10 3993/4885
US-20220298114-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES SI, MLN, MLNR MEN1 295/4885KMT2A 1454/4885HSD17B10 3993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.