Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405947 | 0.85 | RAB9A (0.50) | SMN1; SMN2POLBRAB9AL3MBTL1ATM | |
| SCHEMBL4415031 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBRAB9AL3MBTL1ATM | |
| SCHEMBL4414653 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBRAB9AL3MBTL1ATM | |
| SCHEMBL4638378 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBRAB9AL3MBTL1ATM | |
| SCHEMBL4405730 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBRAB9AL3MBTL1ATM | |
| SCHEMBL4617609 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2POLBRAB9AL3MBTL1ATM | |
| SCHEMBL4403726 | 0.74 | RAB9A (0.58) | SMN1; SMN2RAB9AL3MBTL1ATMNPC1 | |
| SCHEMBL9137872 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBRAB9AL3MBTL1NPC1 | |
| Propionic Acid SCHEMBL10593320 | 0.71 | POLB (0.64) | SMN1; SMN2POLBRAB9AL3MBTL1HPGD | |
| SCHEMBL5798568 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2POLBRAB9AL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |