Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL10593320 | 0.87 | POLB (0.64) | SMN1; SMN2POLBRAB9AL3MBTL1AOC3 | |
| SCHEMBL4617609 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2POLBRAB9AL3MBTL1NPC1 | |
| SCHEMBL9078674 | 0.83 | AOC3 (0.48) | SMN1; SMN2POLBRAB9AL3MBTL1AOC3 | |
| SCHEMBL6601841 | 0.81 | AOC3 (0.47) | SMN1; SMN2POLBRAB9AL3MBTL1AOC3 | |
| SCHEMBL6507597 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBRAB9AL3MBTL1AOC3 | |
| SCHEMBL4638106 | 0.81 | AOC3 (0.44) | SMN1; SMN2POLBRAB9AL3MBTL1AOC3 | |
| SCHEMBL9079266 | 0.81 | AOC3 (0.47) | SMN1; SMN2POLBRAB9AL3MBTL1AOC3 | |
| SCHEMBL22231486 | 0.81 | AOC3 (0.47) | SMN1; SMN2POLBRAB9AL3MBTL1AOC3 | |
| SCHEMBL20714306 | 0.81 | AOC3 (0.50) | SMN1; SMN2POLBRAB9AL3MBTL1AOC3 | |
| SCHEMBL6601376 | 0.81 | AOC3 (0.50) | SMN1; SMN2POLBRAB9AL3MBTL1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593332-B1 | Phenylborinic acid derivatives, their preparation and their use as intermediates in syntheses | SYNTHELABO (FR) | 1998-01-14 | — | — | EP | claimed |
| US-5382672-A | Preparation of derivatives of benzeneborinic acid | SYNTHELABO (FR) | 1995-01-17 | — | — | US | claimed |
| EP-0593332-A1 | Phenylboronic acid derivatives, their preparation and their use as intermediates in syntheses | SYNTHELABO (FR) | 1994-04-20 | — | — | EP | claimed |
| JP-6192240-A | — | — | None | — | — | JP | disclosed |
| US-10407422-B2 | Triazolopyridine inhibitors of myeloperoxidase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-09-10 | — | — | US | disclosed |
| US-20190023701-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL MYERS SQUIBB CO (US) | 2019-01-24 | — | — | US | disclosed |
| CN-104395326-B | Process for producing borinic acid derivative and novel borinic acid derivative | 玛耐科股份有限公司 | 2017-04-05 | — | — | CN | disclosed |
| EP-2886548-A1 | METHOD FOR PRODUCING BORINIC ACID DERIVATIVE, AND NOVEL BORINIC ACID DERIVATIVE | Manac Inc. (JP) | 2015-06-24 | — | — | EP | disclosed |
| US-20150105562-A1 | METHOD FOR PREPARING BORINIC ACID DERIVATIVES AND NOVEL BORINIC ACID DERIVATIVES | MANAC INC. (JP) | 2015-04-16 | — | — | US | disclosed |
| CN-104395326-A | Process for producing borinic acid derivative and novel borinic acid derivative | MANAC INC | 2015-03-04 | — | — | CN | disclosed |
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-5476941-A | 2-[2-(5-tetrazolyl)phenyl]-1,2-dihydroquinoline derivatives | SYNTHELABO (FR) | 1995-12-19 | — | — | US | disclosed |
| EP-0655452-A1 | Triarylborane derivatives, their preparation and their use as intermediates | SYNTHELABO (FR) | 1995-05-31 | — | — | EP | disclosed |
| US-5405960-A | Triarylborane derivatives, their preparation and their use as synthesis intermediates | SYNTHELABO (FR) | 1995-04-11 | — | — | US | disclosed |
| EP-0646581-A1 | 2-(2-Tetrazol-5-yl)phenyl)-1,2-dihydroquinoline derivatives and their use as intermediates | SYNTHELABO (FR) | 1995-04-05 | — | — | EP | disclosed |
| US-5382672-A | Preparation of derivatives of benzeneborinic acid | SYNTHELABO (FR) | 1995-01-17 | — | — | US | disclosed |
| US-5374735-A | Triarylborane derivatives, their preparation and their use as synthesis intermediates | SYNTHELABO (FR) | 1994-12-20 | — | — | US | disclosed |
| JP-H06192240-A | BENZENEBORINIC ACID DERIVATIVE, PREPARATION THEREOF AND USE THEREOF AS SYNTHETIC INTERMEDIATE | SYNTHELABO SA | 1994-07-12 | — | — | JP | disclosed |
| EP-0593332-A1 | Phenylboronic acid derivatives, their preparation and their use as intermediates in syntheses | SYNTHELABO (FR) | 1994-04-20 | — | — | EP | disclosed |
| US-5278312-A | Derivatives of benzeneborinic acid, preparation thereof and use thereof as synthetic intermediates | SYNTHELABO (FR) | 1994-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023701-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | EPX, MPO, SERPINB1 | SMN1; SMN2 4661/4885POLB 1095/4885RAB9A 3993/4885 |
| US-20150105562-A1 | METHOD FOR PREPARING BORINIC ACID DERIVATIVES AND NOVEL BORINIC ACID DERIVATIVES | ADORA2B, TPSAB1, ACVR2B | SMN1; SMN2 1879/4885POLB 1316/4885RAB9A 902/4885 |
| US-10407422-B2 | Triazolopyridine inhibitors of myeloperoxidase | EPX, MPO, SERPINB1 | SMN1; SMN2 4661/4885POLB 1095/4885RAB9A 3993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.