Macrocarpal C

Macrocarpal C

SCHEMBL4411392

C=C1CCC2C(C3C1CCC3(C)C(CC(C)C)c1c(O)c(C=O)c(O)c(C=O)c1O)C2(C)C

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 16/20 0.68
PLA2R1 Q13018 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Macrocarpal C SCHEMBL136282 1.00 PTPN1 (0.68) PTPN1PLA2R1
Macrocarpal C SCHEMBL96125 1.00 PTPN1 (0.68) PTPN1PLA2R1
Macrocarpal C SCHEMBL23484420 1.00 PTPN1 (0.68) PTPN1PLA2R1
Macrocarpal C SCHEMBL4419114 1.00 PTPN1 (0.68) PTPN1PLA2R1
SCHEMBL12549609 0.92 PTPN1 (0.61) PTPN1PLA2R1
Macrocarpal A SCHEMBL96222 0.81 PTPN1 (1.00) PTPN1PLA2R1
Macrocarpal A SCHEMBL13597681 0.81 PTPN1 (1.00) PTPN1PLA2R1
Macrocarpal A SCHEMBL13597677 0.81 PTPN1 (1.00) PTPN1PLA2R1
Macrocarpal A SCHEMBL4413981 0.81 PTPN1 (1.00) PTPN1PLA2R1
Macrocarpal A SCHEMBL23484425 0.81 PTPN1 (1.00) PTPN1PLA2R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090324754-A1 EUCALYPTUS EXTRACT, METHOD OF PREPARATION AND THERAPEUTIC USES THEREOF PIERRE FABRE MEDICAMENT (FR) 2009-12-31 US claimed
US-20090324754-A1 EUCALYPTUS EXTRACT, METHOD OF PREPARATION AND THERAPEUTIC USES THEREOF PIERRE FABRE MEDICAMENT (FR) 2009-12-31 US disclosed
US-20090324754-A1 EUCALYPTUS EXTRACT, METHOD OF PREPARATION AND THERAPEUTIC USES THEREOF PIERRE FABRE MEDICAMENT (FR) 2009-12-31 US disclosed
US-20090324754-A1 EUCALYPTUS EXTRACT, METHOD OF PREPARATION AND THERAPEUTIC USES THEREOF PIERRE FABRE MEDICAMENT (FR) 2009-12-31 US disclosed
WO-2008017752-A2 EUCALYPTUS EXTRACT, METHOD OF PREPARATION AND THERAPEUTIC USES THEREOF PIERRE FABRE MEDICAMENT (FR) 2008-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090324754-A1 EUCALYPTUS EXTRACT, METHOD OF PREPARATION AND THERAPEUTIC USES THEREOF NMUR2, NMUR1, NMBR PTPN1 4527/4885PLA2R1 1686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.