Macrocarpal C

Macrocarpal C

SCHEMBL136282

C=C1CC[C@@H]2[C@H]([C@H]3[C@H]1CC[C@]3(C)[C@@H](CC(C)C)c1c(O)c(C=O)c(O)c(C=O)c1O)C2(C)C

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 16/20 0.68
PLA2R1 Q13018 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Macrocarpal C SCHEMBL96125 1.00 PTPN1 (0.68) PTPN1PLA2R1
Macrocarpal C SCHEMBL23484420 1.00 PTPN1 (0.68) PTPN1PLA2R1
Macrocarpal C SCHEMBL4411392 1.00 PTPN1 (0.68) PTPN1PLA2R1
Macrocarpal C SCHEMBL4419114 1.00 PTPN1 (0.68) PTPN1PLA2R1
SCHEMBL12549609 0.92 PTPN1 (0.61) PTPN1PLA2R1
Macrocarpal A SCHEMBL96222 0.81 PTPN1 (1.00) PTPN1PLA2R1
Macrocarpal A SCHEMBL13597681 0.81 PTPN1 (1.00) PTPN1PLA2R1
Macrocarpal A SCHEMBL13597677 0.81 PTPN1 (1.00) PTPN1PLA2R1
Macrocarpal A SCHEMBL4413981 0.81 PTPN1 (1.00) PTPN1PLA2R1
Macrocarpal A SCHEMBL23484425 0.81 PTPN1 (1.00) PTPN1PLA2R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240327291-A1 MULTIVALENT MANGANESE OXIDE FILLER, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF UNIV CHONGQING (CN) 2024-10-03 US disclosed
US-9402407-B2 Method for preparation of eucalyptus extract LOTTE CO., LTD. (JP) 2016-08-02 US disclosed
US-20120058172-A1 PLANT EXTRACTS FOR USE IN BRAIN MODULATION INTERMED DISCOVERY GMBH (DE) 2012-03-08 US disclosed
US-20110129554-A1 Method For Preparation Of Eucalyptus Extract LOTTE CO., LTD. (JP) 2011-06-02 US disclosed
US-20110021613-A1 PLANTS EXTRACTS FOR USE IN BRAIN MODULATION INTERMED DISCOVERY GMBH (DE) 2011-01-27 US disclosed
US-20090324754-A1 EUCALYPTUS EXTRACT, METHOD OF PREPARATION AND THERAPEUTIC USES THEREOF PIERRE FABRE MEDICAMENT (FR) 2009-12-31 US disclosed
US-20090324754-A1 EUCALYPTUS EXTRACT, METHOD OF PREPARATION AND THERAPEUTIC USES THEREOF PIERRE FABRE MEDICAMENT (FR) 2009-12-31 US disclosed
EP-1939166-A1 Plants extracts for use in brain modulation InterMed Discovery GmbH (DE) 2008-07-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090324754-A1 EUCALYPTUS EXTRACT, METHOD OF PREPARATION AND THERAPEUTIC USES THEREOF NMUR2, NMUR1, NMBR PTPN1 4527/4885PLA2R1 1686/4885
US-20110129554-A1 Method For Preparation Of Eucalyptus Extract TAS2R7, OR10J3, TAS2R16 PTPN1 4298/4885PLA2R1 2463/4885
US-20110021613-A1 PLANTS EXTRACTS FOR USE IN BRAIN MODULATION PYGB, FABP7, LANCL1 PTPN1 3670/4885PLA2R1 2001/4885
US-20120058172-A1 PLANT EXTRACTS FOR USE IN BRAIN MODULATION PYGB, FABP7, LANCL1 PTPN1 3808/4885PLA2R1 1998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.