Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13548896 | 1.00 | KDM5A (0.65) | KDM5AMAPTKDM4EMEN1KMT2A | |
| SCHEMBL13550629 | 0.91 | KDM5A (0.65) | KDM5AMAPTKDM4EMEN1KMT2A | |
| SCHEMBL13548902 | 0.91 | KDM5A (0.67) | KDM5AMAPTKDM4EMEN1KMT2A | |
| SCHEMBL4405047 | 0.91 | KDM5A (0.52) | KDM5AMAPTKDM4EMEN1KMT2A | |
| SCHEMBL13548899 | 0.90 | KDM5A (0.60) | KDM5AMAPTKDM4EMEN1KMT2A | |
| SCHEMBL13548874 | 0.90 | KDM5A (0.60) | KDM5AMAPTKDM4EMEN1KMT2A | |
| SCHEMBL14149136 | 0.89 | KDM5A (0.65) | KDM5AMAPTKDM4EMEN1KMT2A | |
| SCHEMBL14045958 | 0.89 | KDM5A (0.65) | KDM5AMAPTKDM4EMEN1KMT2A | |
| SCHEMBL4404326 | 0.89 | KDM5A (0.50) | KDM5AMAPTKDM4EMEN1KMT2A | |
| SCHEMBL13548913 | 0.87 | KDM5A (0.65) | KDM5AMAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11839617-B2 | Theramutein modulators | HMI Medical Innovations, LLC (US) | 2023-12-12 | — | — | US | disclosed |
| US-11839617-B2 | Theramutein modulators | HMI Medical Innovations, LLC (US) | 2023-12-12 | — | — | US | disclosed |
| US-11714080-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2023-08-01 | — | — | US | disclosed |
| US-11714080-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2023-08-01 | — | — | US | disclosed |
| US-11692998-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2023-07-04 | — | — | US | disclosed |
| US-11692998-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2023-07-04 | — | — | US | disclosed |
| US-20210215670-A1 | COMPOUNDS AND METHODS OF IDENTIFYING, SYNTHESIZING, OPTIMIZING AND PROFILING PROTEIN MODULATORS | HMI Medical Innovations, LLC | 2021-07-15 | — | — | US | disclosed |
| US-20210215671-A1 | COMPOUNDS AND METHODS OF IDENTIFYING, SYNTHESIZING, OPTIMIZING AND PROFILING PROTEIN MODULATORS | HMI Medical Innovations, LLC | 2021-07-15 | — | — | US | disclosed |
| US-10955408-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2021-03-23 | — | — | US | disclosed |
| US-20210015825-A1 | THERAMUTEIN MODULATORS | HMI Medical Innovations, LLC | 2021-01-21 | — | — | US | disclosed |
| EP-2447252-A2 | Theramutein modulators | Housey, Gerard M. (US) | 2012-05-02 | — | — | EP | disclosed |
| US-20100016298-A1 | Theramutein modulators | HOUSEY GERAD M | 2010-01-21 | — | — | US | disclosed |
| US-20100016298-A1 | Theramutein modulators | HOUSEY GERAD M | 2010-01-21 | — | — | US | disclosed |
| US-20090275070-A1 | Compounds and Methods of Identifying, Synthesizing, Optimizing and Profiling Protein Modulators | HOUSEY GERARD M | 2009-11-05 | — | — | US | disclosed |
| US-20090275070-A1 | Compounds and Methods of Identifying, Synthesizing, Optimizing and Profiling Protein Modulators | HOUSEY GERARD M | 2009-11-05 | — | — | US | disclosed |
| US-20080269262-A1 | Blocking or activation of endogenous proteins variations rncoded by mutated gees | HMI MEDICAL INNOVATIONS, LLC. | 2008-10-30 | — | — | US | disclosed |
| US-20080269262-A1 | Blocking or activation of endogenous proteins variations rncoded by mutated gees | HMI MEDICAL INNOVATIONS, LLC. | 2008-10-30 | — | — | US | disclosed |
| WO-2008091681-A2 | THERAMUTEIN MODULATORS | HOUSEY GERARD M (US) | 2008-07-31 | — | — | WO | disclosed |
| US-20070111199-A1 | Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC | 2007-05-17 | — | — | US | disclosed |
| US-20070111199-A1 | Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016298-A1 | Theramutein modulators | TSG101, SERPINE1, PLAUR | KDM5A 4434/4885MAPT 2984/4885KDM4E 4221/4885 |
| US-20210015825-A1 | THERAMUTEIN MODULATORS | TSG101, SERPINE1, PLAUR | KDM5A 4434/4885MAPT 2984/4885KDM4E 4221/4885 |
| US-11839617-B2 | Theramutein modulators | TSG101, SERPINE1, PLAUR | KDM5A 4434/4885MAPT 2984/4885KDM4E 4221/4885 |
| US-20080269262-A1 | Blocking or activation of endogenous proteins variations rncoded by mutated gees | SERBP1, SERPINA6, UBE2V1 | KDM5A 3794/4885MAPT 4644/4885KDM4E 4172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.