SCHEMBL4412136

SCHEMBL4412136

NNC(=O)CCN1C=CCC1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.49
POLB P06746 1/20 0.44
HTT P42858 1/20 0.44
LMNA P02545 1/20 0.42
KMT2A Q03164 1/20 0.42
KDM4E B2RXH2 2/20 0.36
CTSD P07339 1/20 0.36
KDM5C P41229 1/20 0.36
PHF8 Q9UPP1 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4412114 0.77 MAPT (0.50) MAPTPOLBHTTLMNAKMT2A
SCHEMBL2113300 0.77 GLA (0.38) MAPTPOLBLMNAKMT2AKDM4E
SCHEMBL15047584 0.71
SCHEMBL4411242 0.70 MAPT (0.47) MAPTPOLBHTTLMNAKMT2A
SCHEMBL4419502 0.70 MAPT (0.80) MAPTPOLBHTTLMNAKMT2A
SCHEMBL191999 0.69
SCHEMBL4992871 0.68
SCHEMBL2943510 0.68
SCHEMBL31397816 0.67
SCHEMBL10503984 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100587001-C Polyacetal resin composition POLYPLASTICS CO 2010-02-03 CN disclosed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
CN-1878834-A Polyacetal resin composition POLYPLASTICS CO (JP) 2006-12-13 CN disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed