Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22703043 | 0.92 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL21791166 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL21791068 | 0.85 | HPRT1 (0.46) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL28671989 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL21791050 | 0.79 | TSHR (0.51) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL21298140 | 0.79 | ANPEP (0.44) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL22650788 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL21297893 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL21298448 | 0.77 | KDM4E (0.40) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL21298261 | 0.77 | ANPEP (0.45) | ALDH1A1KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524891-B2 | Tetraazaporphyrin-based compounds and their uses | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2013-09-03 | — | — | US | disclosed |
| US-20090215105-A1 | Tetraazaporphyrin-Based Compounds and Their Uses | NATIONAL SCIENCE FOUNDATION | 2009-08-27 | — | — | US | disclosed |
| EP-1912921-A2 | TETRAAZAPORPHYRIN-BASED COMPOUNDS AND THEIR USES | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007009101-A2 | TETRAAZAPORPHYRIN-BASED COMPOUNDS AND THEIR USES | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215105-A1 | Tetraazaporphyrin-Based Compounds and Their Uses | DDB1, PPIF, SSBP1 | ALDH1A1 4116/4885KDM4E 4194/4885HPGD 2418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.