Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4412445 | 0.80 | HTR6 (0.48) | HTR6PKMTSHRMEN1KMT2A | |
| SCHEMBL1996812 | 0.78 | HTR6 (0.48) | HTR6PKMTSHRMEN1KMT2A | |
| SCHEMBL1995765 | 0.76 | HTR6 (0.48) | HTR6DRD2DRD3 | |
| SCHEMBL4413035 | 0.74 | HTR6 (0.51) | HTR6DRD2DRD3 | |
| SCHEMBL1995160 | 0.73 | HTR6 (0.46) | HTR6DRD2DRD3 | |
| SCHEMBL1993429 | 0.71 | HTR6 (0.54) | HTR6PKMTSHRMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL1996241 | 0.70 | HTR6 (0.43) | HTR6DRD2DRD3 | |
| SCHEMBL1997460 | 0.69 | HTR6 (0.41) | HTR6DRD2DRD3 | |
| SCHEMBL1999661 | 0.67 | HTR6 (0.46) | HTR6DRD2DRD3 | |
| SCHEMBL4412448 | 0.67 | HTR6 (0.42) | HTR6PKMTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091953-A1 | 8-SULFONYL-L, 3, 4, 8-TETRAHYDR0-2H- [1, 4]OXAZEPINO [6, 7-E]INDOLE DERIVATIVES AND THEIR USE AS 5-HT6 RECEPTOR LIGANDS | BIOVITRUM AB (publ) (SE) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008054288-A1 | 8-SULFONYL-L, 3, 4, 8-TETRAHYDR0-2H- [1, 4] OXAZEPINO [6, 7-E] INDOLE DERIVATIVES AND THEIR USE AS 5-HT6 RECEPTOR LIGANDS | BIOVITRUM AB (PUBL) (SE) | 2008-05-08 | — | — | WO | disclosed |