Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 5/20 | 0.55 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 12/20 | 0.46 |
| ▸ | FNTB | P49356 | 12/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097459 | 0.78 | GRIA4 (0.49) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL3818516 | 0.78 | GRIA4 (0.57) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL1551995 | 0.78 | GRIA4 (0.57) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL7815351 | 0.77 | GRIA4 (0.50) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL4422079 | 0.77 | GRIA4 (0.51) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL10653341 | 0.73 | GRIA4 (0.94) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL4418655 | 0.73 | FNTA (0.34) | GRIA4GRIA2FNTAFNTB | |
| SCHEMBL9096920 | 0.72 | GRIA4 (0.42) | GRIA4GRIA2FNTAFNTBKMT2A | |
| SCHEMBL9865620 | 0.72 | GRIA4 (0.45) | GRIA4FNTAFNTBKMT2AALDH1A1 | |
| SCHEMBL3126194 | 0.71 | GRIA4 (0.80) | GRIA4GRIA2FNTAFNTBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325925-A1 | Thiophenes and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325925-A1 | Thiophenes and uses thereof | PIK3CA, JAK2, MTOR | GRIA4 2350/4885GRIA2 2570/4885FNTA 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.