Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505807 | 0.92 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19SLC6A2TAAR1 | |
| SCHEMBL27537772 | 0.79 | CYP1A2 (0.37) | CYP1A2CYP2C9CYP2C19SLC6A2TAAR1 | |
| SCHEMBL2785385 | 0.79 | KCNA5 (0.40) | CYP1A2CYP2C9CYP2C19SLC6A2TAAR1 | |
| SCHEMBL29548659 | 0.76 | KCNN4 (0.38) | CYP1A2CYP2C9CYP2C19SLC6A2TAAR1 | |
| SCHEMBL3663149 | 0.76 | CYP1A2 (0.45) | CYP1A2CYP2C9CYP2C19SLC6A2TAAR1 | |
| SCHEMBL7166697 | 0.75 | RXRA (0.48) | KCNN4CES1SMN1; SMN2 | |
| SCHEMBL765190 | 0.75 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19SLC6A2TAAR1 | |
| SCHEMBL11409113 | 0.74 | KCNN4 (0.43) | TAAR1LMNAKCNN4MAPK1CES1 | |
| SCHEMBL8072762 | 0.74 | KCNN4 (0.43) | TAAR1LMNAKCNN4MAPK1CES1 | |
| SCHEMBL16144806 | 0.72 | KCNN4 (0.42) | TAAR1LMNAKCNN4KIF11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620451-A4 | INDUSTRIALLY SCALABLE NUCLEOSIDE SYNTHESIS | NOVARTIS AG (CH) | 2009-02-18 | — | — | EP | disclosed |
| EP-1620451-A2 | INDUSTRIALLY SCALABLE NUCLEOSIDE SYNTHESIS | Idenix (Cayman) Limited (KY) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004096149-A2 | INDUSTRIALLY SCALABLE NUCLEOSIDE SYNTHESIS | IDENIX (CAYMAN) LIMITED (KY) | 2004-11-11 | — | — | WO | disclosed |