Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.76 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435165 | 0.87 | MAPK9 (0.59) | MAPK9MAPK10MEN1KMT2ANPC1 | |
| SCHEMBL1518774 | 0.87 | MAPK9 (1.00) | MAPK9MAPK10MEN1KMT2ANPC1 | |
| SCHEMBL2420683 | 0.79 | MAPK9 (0.85) | MAPK9MAPK10MEN1KMT2ARXFP1 | |
| SCHEMBL2421884 | 0.79 | MAPK9 (0.85) | MAPK9MAPK10MEN1KMT2ACYP2D6 | |
| SCHEMBL13198016 | 0.77 | MAPK9 (0.77) | MAPK9MAPK10MEN1KMT2ANPC1 | |
| SCHEMBL2422524 | 0.77 | MAPK9 (0.81) | MAPK9MAPK10MEN1KMT2ARXFP1 | |
| SCHEMBL2422088 | 0.77 | MAPK9 (0.81) | MAPK9MAPK10MEN1KMT2ACYP2D6 | |
| SCHEMBL2422218 | 0.76 | MAPK9 (0.80) | MAPK9MAPK10MEN1KMT2ANPC1 | |
| SCHEMBL4970923 | 0.76 | MAPK9 (0.79) | MAPK9MAPK10MEN1KMT2ACYP2D6 | |
| SCHEMBL2425364 | 0.76 | MAPK9 (0.80) | MAPK9MAPK10MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218375-B1 | PHARMACEUTICALLY ACTIVE SULFONYL AMINO ACID DERIVATIVES | MERCK SERONO SA (CH) | 2009-08-26 | — | — | EP | claimed |
| EP-1218375-B1 | PHARMACEUTICALLY ACTIVE SULFONYL AMINO ACID DERIVATIVES | MERCK SERONO SA (CH) | 2009-08-26 | — | — | EP | disclosed |