Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413374 | 0.87 | MAPK9 (0.76) | MAPK9MAPK10USP2L3MBTL1MEN1 | |
| SCHEMBL1518950 | 0.83 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2ARXFP1NPSR1 | |
| SCHEMBL1518774 | 0.76 | MAPK9 (1.00) | MAPK9MAPK10USP2L3MBTL1MEN1 | |
| SCHEMBL7436716 | 0.73 | MAPK9 (0.58) | MAPK9MAPK10USP2L3MBTL1MEN1 | |
| SCHEMBL3543855 | 0.72 | P2RX1 (0.40) | MAPK9MAPK10L3MBTL1MEN1KMT2A | |
| SCHEMBL2419901 | 0.71 | MAPK9 (0.78) | MAPK9MAPK10USP2L3MBTL1MEN1 | |
| SCHEMBL2423342 | 0.70 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2ALMNA | |
| SCHEMBL13198016 | 0.70 | MAPK9 (0.77) | MAPK9MAPK10USP2L3MBTL1MEN1 | |
| SCHEMBL2421884 | 0.70 | MAPK9 (0.85) | MAPK9MAPK10USP2MEN1KMT2A | |
| SCHEMBL2420683 | 0.70 | MAPK9 (0.85) | MAPK9MAPK10USP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218375-A1 | PHARMACEUTICALLY ACTIVE SULFONYL AMINO ACID DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | claimed |
| WO-2001023379-A1 | PHARMACEUTICALLY ACTIVE SULFONYL AMINO ACID DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | claimed |
| WO-1996037485-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1996-11-28 | — | — | WO | disclosed |