Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411744 | 0.81 | GLA (0.49) | GLASLC6A2SLC6A4FOLH1DPP7 | |
| SCHEMBL4496028 | 0.79 | GLA (0.57) | GLASLC6A2SLC6A4FOLH1DPP7 | |
| SCHEMBL5262783 | 0.79 | GLA (0.57) | GLASLC6A2SLC6A4FOLH1DPP7 | |
| SCHEMBL2660512 | 0.77 | GLA (0.58) | GLASLC6A2SLC6A4FOLH1DPP7 | |
| SCHEMBL4410263 | 0.77 | GLA (0.40) | GLASLC6A2SLC6A4FOLH1DPP7 | |
| SCHEMBL4420077 | 0.75 | AKT1 (0.40) | GLASLC6A2SLC6A4FOLH1DPP7 | |
| SCHEMBL21316490 | 0.74 | GLA (0.55) | GLASLC6A2SLC6A4FOLH1DPP7 | |
| SCHEMBL28046794 | 0.74 | GLA (0.55) | GLASLC6A2SLC6A4FOLH1DPP7 | |
| SCHEMBL20170038 | 0.73 | GLA (0.54) | GLASLC6A2SLC6A4FOLH1DPP7 | |
| SCHEMBL800275 | 0.73 | GLA (0.54) | GLASLC6A2SLC6A4SCN8AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040698-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |