Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046794 | 0.82 | GLA (0.55) | GLAFOLH1MAOBSLC6A2SLC6A4 | |
| SCHEMBL4413465 | 0.81 | GLA (0.48) | GLAFOLH1MAOBSLC6A2SLC6A4 | |
| SCHEMBL2660512 | 0.79 | GLA (0.58) | GLAFOLH1MAOBSLC6A2SLC6A4 | |
| SCHEMBL4496028 | 0.77 | GLA (0.57) | GLAFOLH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5262783 | 0.77 | GLA (0.57) | GLAFOLH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21316490 | 0.76 | GLA (0.55) | GLAFOLH1MAOBSLC6A2SLC6A4 | |
| SCHEMBL22395447 | 0.76 | FOLH1 (0.50) | GLAFOLH1SLC6A2SLC6A4FFAR1 | |
| SCHEMBL10606037 | 0.76 | FOLH1 (0.50) | GLAFOLH1SLC6A2SLC6A4FFAR1 | |
| SCHEMBL6666068 | 0.75 | HRH3 (0.58) | GLAFOLH1MAOBSLC6A2SLC6A4 | |
| SCHEMBL3495199 | 0.75 | TRPA1 (0.50) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040698-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |