Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413465 | 0.75 | GLA (0.48) | AKT1FOLH1GLADPP4DPP7 | |
| SCHEMBL4691003 | 0.72 | DPP7 (0.43) | AKT1FFAR1FFAR4FOLH1GLA | |
| SCHEMBL4387350 | 0.71 | FFAR1 (0.38) | AKT1FFAR1FFAR4MAOBKCNH2 | |
| SCHEMBL4410263 | 0.70 | GLA (0.40) | AKT1FOLH1GLADPP4DPP7 | |
| SCHEMBL5721115 | 0.69 | DPP4 (0.41) | AKT1FFAR1FFAR4FOLH1GLA | |
| SCHEMBL4496028 | 0.69 | GLA (0.57) | FOLH1GLADPP4DPP7DPP9 | |
| SCHEMBL5262783 | 0.69 | GLA (0.57) | FOLH1GLADPP4DPP7DPP9 | |
| SCHEMBL10606037 | 0.67 | FOLH1 (0.50) | AKT1FFAR1FFAR4FOLH1GLA | |
| SCHEMBL22395447 | 0.67 | FOLH1 (0.50) | AKT1FFAR1FFAR4FOLH1GLA | |
| SCHEMBL923535 | 0.67 | ALOX5 (0.50) | FFAR1FFAR4SLC6A2SLC6A4MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040698-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |