Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17244592 | 0.90 | ALDH1A1 (0.52) | TSHRALDH1A1LMNACYP4F2CYP4A11 | |
| SCHEMBL6152498 | 0.88 | ALDH1A1 (0.43) | TSHRALDH1A1LMNACYP4F2CYP4A11 | |
| SCHEMBL10438855 | 0.87 | CYP4F2 (0.58) | TSHRALDH1A1LMNACYP4F2CYP4A11 | |
| SCHEMBL3623804 | 0.81 | CYP1A2 (0.54) | TSHRALDH1A1LMNACYP4F2CYP4A11 | |
| SCHEMBL30776972 | 0.81 | CYP1A2 (0.54) | TSHRALDH1A1LMNACYP4F2CYP4A11 | |
| SCHEMBL18802064 | 0.81 | CYP4F2 (0.57) | TSHRALDH1A1LMNACYP4F2CYP4A11 | |
| SCHEMBL8914213 | 0.80 | CYP4F2 (0.51) | TSHRALDH1A1LMNACYP4F2CYP4A11 | |
| SCHEMBL22954711 | 0.80 | CYP4F2 (0.56) | TSHRALDH1A1LMNACYP4F2CYP4A11 | |
| SCHEMBL6240139 | 0.80 | KDM4E (0.50) | TSHRALDH1A1LMNACYP4F2CYP4A11 | |
| SCHEMBL29852765 | 0.80 | NPC1 (0.52) | TSHRALDH1A1LMNACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372184-A | Method for synthesizing C-N axis chiral phenanthridinone compound based on chiral transfer strategy | 武汉大学 | 2021-09-10 | — | — | CN | disclosed |
| CN-109776295-A | A kind of aryl iodine compound and preparation method of the ortho position containing difluoro methylene | 浙江师范大学 | 2019-05-21 | — | — | CN | disclosed |
| US-20090231240-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE | FUJI XEROX CO., LTD. (JP) | 2009-09-17 | — | — | US | disclosed |