SCHEMBL4413738

SCHEMBL4413738

NNC(=O)CCN(CCC(=O)NN)CCC(=O)NN

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
CTSD P07339 1/20 0.52
KDM5C P41229 1/20 0.52
PHF8 Q9UPP1 1/20 0.52
KDM2A Q9Y2K7 1/20 0.52
ALDH1A1 P00352 3/20 0.42
LMNA P02545 2/20 0.42
MAPT P10636 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
GAA P10253 3/20 0.38
CYP1A2 P05177 4/20 0.36
CYP3A4 P08684 3/20 0.36
CYP2C19 P33261 3/20 0.36
CYP2D6 P10635 2/20 0.36
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
ICMT O60725 1/20 0.33
ALB P02768 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4410149 0.91 KDM4E (0.44) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL961501 0.89 CTSD (0.60) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL962174 0.85 CTSD (0.56) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL4417440 0.85 CTSD (0.56) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL519337 0.79
SCHEMBL4421119 0.79 CTSD (0.35) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL220310 0.78 KDM4E (0.77) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL25586129 0.76 PTGS1 (0.40) KDM4ECTSDKDM5CPHF8KDM2A
Hydrazine SCHEMBL28064827 0.76 KDM4E (0.72) KDM4ECTSDKDM5CPHF8KDM2A
SCHEMBL960137 0.75 CTSD (0.56) KDM4ECTSDKDM5CPHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240043705-A1 MODIFIED POLYCARBODIIMIDE COMPOUND, COATING COMPOSITION AND COATED ARTICLE Sherwin-Williams (Guangdong) New Material Co., Ltd. (CN) 2024-02-08 US disclosed
US-20240010853-A1 COATING COMPOSITION AND COATED ARTICLE INCLUDING COATING FORMED BY THE COATING COMPOSITION Sherwin-Williams (Guangdong) New Material Co., Ltd. (CN) 2024-01-11 US disclosed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed
US-5874417-A A CROSSLINKED COMPOSITION HAVING CONJUGATED SITE AT GLUCURONIC ACID WITH A MONO HYDRAZIDE OR A POLYHYDRAZIDE AND A PLURALITY OF CELLS FOR TISSUE ENGINEERING, A COSMETIC AGENT, AND A DRUG; DRUG DELIVERY THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1999-02-23 US disclosed