SCHEMBL962174

SCHEMBL962174

CCN(CC)CCC(=O)NN

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.56
KDM4E B2RXH2 2/20 0.44
KDM5C P41229 1/20 0.44
PHF8 Q9UPP1 1/20 0.44
KDM2A Q9Y2K7 1/20 0.44
TERT O14746 8/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TSHR P16473 2/20 0.41
PAOX Q6QHF9 1/20 0.39
ALDH1A1 P00352 5/20 0.38
MAPK1 P28482 2/20 0.38
GFER P55789 1/20 0.38
GAA P10253 2/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
DNMT1 P26358 1/20 0.38
RAD52 P43351 1/20 0.38
SMARCA2 P51531 1/20 0.38
LMNA P02545 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL963418 0.87 CTSD (0.52) CTSDKDM4EKDM5CPHF8KDM2A
SCHEMBL4413738 0.85 KDM4E (0.52) CTSDKDM4EKDM5CPHF8KDM2A
SCHEMBL961501 0.84 CTSD (0.60) CTSDKDM4EKDM5CPHF8KDM2A
SCHEMBL4417440 0.81 CTSD (0.56) CTSDKDM4EKDM5CPHF8KDM2A
SCHEMBL8165555 0.79 LMNA (0.44) KDM4ETERTMEN1KMT2ATSHR
SCHEMBL18713492 0.77 FAAH (0.48) TERTMEN1KMT2ATSHRPAOX
SCHEMBL4410149 0.77 KDM4E (0.44) CTSDKDM4EKDM5CPHF8KDM2A
SCHEMBL519337 0.76
SCHEMBL3359467 0.76 CTSD (0.48) CTSDKDM4EKDM5CPHF8KDM2A
SCHEMBL11044286 0.76 TERT (0.41) TERTMEN1KMT2ATSHRPAOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2248833-B1 MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE BRIDGESTONE CORP (JP) 2014-03-26 EP disclosed
US-8389641-B2 Modified diene rubber, production method thereof, and rubber composition and tire using the rubber BRIDGESTONE CORPORATION (JP) 2013-03-05 US disclosed
US-20110003911-A1 MODIFIED DIENE RUBBER, PRODUCTION METHOD THEREOF, AND RUBBER COMPOSITION AND TIRE USING THE RUBBER BRIDGESTONE CORPORATION (JP) 2011-01-06 US disclosed
EP-2248833-A1 MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE Bridgestone Corporation (JP) 2010-11-10 EP disclosed
US-20100249336-A1 MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING SAME, AND RUBBER COMPOSITION AND TIRE USING SUCH A MODIFIED NATURAL RUBBER BRIDGESTONE CORPORATION (JP) 2010-09-30 US disclosed
CN-101842393-A Modified natural rubber, process for producing the same, rubber composition and tire using the same BRIDGESTONE CORP 2010-09-22 CN disclosed
EP-2206730-A1 MODIFIED NATURAL RUBBER, PROCESS FOR PRODUCTION OF THE SAME, AND RUBBER COMPOSITION AND TIRE EACH COMPRISING THE SAME Bridgestone Corporation (JP) 2010-07-14 EP disclosed
US-4437960-A SULFUR VULCANIZATION OF CATIONIC POLYMERS AKZO, N.V. (NL) 1984-03-20 US disclosed