Malonic Acid

Malonic Acid

SCHEMBL4413838

CC(O)N(C)C.O=C(O)CC(=O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.50
SRR Q9GZT4 1/20 0.50
TP53 P04637 1/20 0.38
KDM7A Q6ZMT4 1/20 0.36
PHF8 Q9UPP1 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36
CHRNB2 P17787 4/20 0.35
CHRNA4 P43681 4/20 0.35
CHRNB4 P30926 3/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
PTGS2 P35354 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL4419779 1.00 LDHA (0.50) LDHASRRTP53KDM7APHF8
Malonic Acid SCHEMBL4864852 0.86 LDHA (0.53) LDHASRRTP53SLC22A6CYP2D6
Succinic Acid SCHEMBL1131544 0.83 EGLN1 (0.50) TP53KDM7APHF8KDM2ASLC22A6
Propionic Acid SCHEMBL357729 0.83 FFAR3 (0.56) TP53SLC22A6ALDH1A1TDP1GABRP
Glycolic Acid SCHEMBL357521 0.83 TP53 (0.38) TP53PHF8KDM2ACHRNB2CHRNA4
Succinic Acid SCHEMBL11651200 0.83 EGLN1 (0.50) TP53KDM7APHF8KDM2ASLC22A6
Bicarbonate SCHEMBL1131466 0.82 TP53 (0.47) TP53CHRNB2CHRNA4CHRNB4ALDH1A1
Malonic Acid SCHEMBL30288562 0.82 LDHA (0.64) LDHASRRTP53SLC22A6CYP2D6
Acetic Acid SCHEMBL358311 0.79 FFAR3 (0.47) TP53ALDH1A1MAPTTDP1FFAR3
Oxalic Acid SCHEMBL1131508 0.79 TP53 (0.44) TP53CHRNB2CHRNA4ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1603527-B1 TERPENOID FRAGRANCE COMPONENTS STABILIZED WITH MALONIC ACID SALTS UNILEVER PLC (GB) 2009-02-04 EP disclosed
US-7179772-B2 Extended lathering pillow article for personal care UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) 2007-02-20 US disclosed
EP-1509190-B1 ODOR CONTROL IN AMINE SALT CONTAINING COSMETIC COMPOSITIONS UNILEVER PLC (GB) 2006-03-08 EP disclosed
US-20050288208-A1 Extended lathering pillow article for personal care UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2005-12-29 US disclosed
EP-1603527-A1 TERPENOID FRAGRANCE COMPONENTS STABILIZED WITH MALONIC ACID SALTS UNILEVER PLC (GB) 2005-12-14 EP disclosed
EP-1509195-A1 SUNSCREEN COSMETIC COMPOSITIONS STORAGE STABILIZED WITH MALONATE SALTS UNILEVER PLC (GB) 2005-03-02 EP disclosed
EP-1509197-A1 COSMETIC COMPOSITIONS CONTAINING SALTS OF MALONIC ACID UNILEVER PLC (GB) 2005-03-02 EP disclosed
EP-1509190-A1 ODOR CONTROL IN AMINE SALT CONTAINING COSMETIC COMPOSITIONS UNILEVER PLC (GB) 2005-03-02 EP disclosed
US-20040202689-A1 Terpenoid fragrance components stabilized with malonic acid salts UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-10-14 US disclosed
WO-2004082652-A1 TERPENOID FRAGRANCE COMPONENTS STABILIZED WITH MALONIC ACID SALTS UNILEVER PLC (GB) 2004-09-30 WO disclosed
US-20040185073-A1 Cosmetic compositions containing salts of malonic acid UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-09-23 US disclosed
US-20040185074-A1 Odor control in amine salt containing cosmetic compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-09-23 US disclosed
US-20040185015-A1 Sunscreen cosmetic compositions storage stabilized with malonate salts UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-09-23 US disclosed
WO-2003099238-A1 ODOR CONTROL IN AMINE SALT CONTAINING COSMETIC COMPOSITIONS UNILEVER PLC (GB) 2003-12-04 WO disclosed
WO-2003099250-A1 SUNSCREEN COSMETIC COMPOSITIONS STORAGE STABILIZED WITH MALONATE SALTS UNILEVER PLC (GB) 2003-12-04 WO disclosed
WO-2003099254-A1 COSMETIC COMPOSITIONS CONTAINING SALTS OF MALONIC ACID UNILEVER PLC (GB) 2003-12-04 WO disclosed