Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.69 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | CYCS | P99999 | 3/20 | 0.54 |
| ▸ | TERT | O14746 | 4/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29724706 | 1.00 | TOP1 (0.69) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL4409175 | 1.00 | TOP1 (0.69) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL4410144 | 1.00 | TOP1 (0.69) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL29883623 | 1.00 | TOP1 (0.69) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL4407506 | 1.00 | TOP1 (0.69) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL27822907 | 0.98 | TOP1 (0.68) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL245937 | 0.93 | TOP1 (0.78) | TOP1CYCSTERTENPP2 | |
| SCHEMBL29961137 | 0.93 | TOP1 (0.78) | TOP1CYCSTERTENPP2 | |
| SCHEMBL31313616 | 0.91 | TOP1 (0.76) | TOP1CYCSTERTENPP2 | |
| SCHEMBL31313917 | 0.91 | TOP1 (0.76) | TOP1CYCSTERTENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053812-B | Metal iridium-containing single pyridyl porphyrin crystal material and preparation method thereof | 江苏大学 | 2020-08-28 | — | — | CN | claimed |
| CN-102180883-A | Substituted porphyrin gold (III) compounds with anticancer activity and preparation method thereof | UNIV YANGZHOU | 2011-09-14 | — | — | CN | claimed |
| CN-113444099-B | Reaction type hydrogen sulfide fluorescent probe and preparation and application thereof | 浙江大学城市学院 | 2022-06-21 | — | — | CN | disclosed |
| CN-113444099-A | Reaction type hydrogen sulfide fluorescent probe and preparation and application thereof | 浙江大学城市学院 | 2021-09-28 | — | — | CN | disclosed |
| CN-109053812-B | Metal iridium-containing single pyridyl porphyrin crystal material and preparation method thereof | 江苏大学 | 2020-08-28 | — | — | CN | disclosed |
| CN-109053812-B | Metal iridium-containing single pyridyl porphyrin crystal material and preparation method thereof | 江苏大学 | 2020-08-28 | — | — | CN | disclosed |
| CN-102167704-B | Water-soluble porphyrin gold (III) anticancer compounds and preparation method thereof | UNIV YANGZHOU | 2014-05-14 | — | — | CN | disclosed |
| CN-102180883-B | Substituted porphyrin gold (III) compounds with anticancer activity and preparation method thereof | UNIV YANGZHOU | 2013-04-17 | — | — | CN | disclosed |
| US-8071760-B2 | Boron-containing porphyrin compounds and their uses | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2011-12-06 | — | — | US | disclosed |
| CN-102180883-A | Substituted porphyrin gold (III) compounds with anticancer activity and preparation method thereof | UNIV YANGZHOU | 2011-09-14 | — | — | CN | disclosed |
| CN-102167704-A | Water-soluble porphyrin gold (III) anticancer compounds and preparation method thereof | UNIV YANGZHOU | 2011-08-31 | — | — | CN | disclosed |
| US-20090318680-A1 | Boron-Containing Porphyrin Compounds and Their Uses | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2009-12-24 | — | — | US | disclosed |
| EP-1940416-A2 | BORON-CONTAINING PORPHYRIN COMPOUNDS AND THEIR USES | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007050564-A2 | BORON-CONTAINING PORPHYRIN COMPOUNDS AND THEIR USES | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318680-A1 | Boron-Containing Porphyrin Compounds and Their Uses | HMBS, HCCS, PPOX | TOP1 816/4885STAT3 3344/4885STAT1 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.