Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423211 | 0.95 | PDE2A (0.54) | PDE2APDE4DTP53MAPTFYN | |
| SCHEMBL4424399 | 0.90 | PDE2A (0.60) | PDE2APDE4DTP53MAPTFYN | |
| SCHEMBL4412620 | 0.88 | PDE2A (0.60) | PDE2APDE4DTP53MAPTFYN | |
| SCHEMBL4411561 | 0.88 | PDE2A (0.58) | PDE2ATP53MAPTFYNPTGDR2 | |
| SCHEMBL4412658 | 0.86 | PDE2A (0.72) | PDE2APDE4DFYNOPRK1KCNH2 | |
| SCHEMBL4602359 | 0.86 | PDE2A (0.58) | PDE2APDE4DTP53MAPTFYN | |
| SCHEMBL4414019 | 0.85 | PDE2A (0.57) | PDE2APDE4DTP53MAPTPTGDR2 | |
| SCHEMBL4410766 | 0.84 | GABRA1 (0.42) | PDE2APDE4DTP53MAPTPTGDR2 | |
| SCHEMBL4423000 | 0.82 | PTGDR2 (0.55) | PDE2ATP53MAPTPTGDR2HTT | |
| SCHEMBL4415654 | 0.80 | PTGDR2 (0.42) | TP53PTGDR2TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749824-A1 | Benzodiazepine derivatives, their preparation and the therapeutic use thereof | NEURO3D (FR) | 2007-02-07 | — | — | EP | claimed |
| US-7599133-B2 | Optical part for camera and method of fabricating the same | SANYO ELECTRIC CO., LTD. (JP) | 2009-10-06 | — | — | US | disclosed |
| US-20090215752-A1 | Compounds, preparation and therapeutic use thereof | BAY CITY CAPITAL LLC | 2009-08-27 | — | — | US | disclosed |
| US-20080204898-A1 | OPTICAL PART FOR CAMERA AND METHOD OF FABRICATING THE SAME | SANYO ELECTRIC CO., LTD. (JP) | 2008-08-28 | — | — | US | disclosed |
| EP-1910315-A2 | BENZODIAZEPINE DERIVATIVES, THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF | NEURO3D (FR) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007026254-A2 | BENZODIAZEPINE DERIVATIVES , THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF | NEURO3D (FR) | 2007-03-08 | — | — | WO | disclosed |
| EP-1749824-A1 | Benzodiazepine derivatives, their preparation and the therapeutic use thereof | NEURO3D (FR) | 2007-02-07 | — | — | EP | disclosed |
| US-6897250-B1 | Automobile interior or exterior trim material | ASAHI DENKA KOGYO K. K. (JP) | 2005-05-24 | — | — | US | disclosed |
| EP-0953596-B1 | Automobile interior or exterior trim material | ASAHI DENKA KOGYO KK (JP) | 2003-10-29 | — | — | EP | disclosed |
| EP-0953596-A2 | Automobile interior or exterior trim material | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1999-11-03 | — | — | EP | disclosed |
| EP-0672619-B1 | Lithium aluminium complex hydroxide salt, blending agent for resin and resin composition | MIZUSAWA INDUSTRIAL CHEM (JP) | 1999-06-02 | — | — | EP | disclosed |
| EP-0672619-A1 | Lithium aluminium complex hydroxide salt, blending agent for resin and resin composition | MIZUSAWA INDUSTRIAL CHEMICALS, LTD. (JP) | 1995-09-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215752-A1 | Compounds, preparation and therapeutic use thereof | PDE12, PDE4B, PDE2A | PDE2A 3/4885PDE4D 13/4885TP53 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.