SCHEMBL4414112

SCHEMBL4414112

C/C=C/C=C(\CC(=O)O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.53
GRIK2 Q13002 2/20 0.53
TSHR P16473 2/20 0.48
KDM4E B2RXH2 1/20 0.48
CPB1 P15086 1/20 0.36
CYP2C19 P33261 1/20 0.35
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35
RECQL P46063 1/20 0.33
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4414116 1.00 GRIK1 (0.53) GRIK1GRIK2TSHRKDM4ECPB1
SCHEMBL24254240 0.81 GRIK1 (0.49) GRIK1GRIK2TSHRKDM4EHSD17B10
SCHEMBL13017674 0.79 GRIK1 (0.40) GRIK1GRIK2TSHRKDM4ERECQL
SCHEMBL16081499 0.79 GRIK1 (0.55) GRIK1GRIK2TSHRKDM4E
SCHEMBL21821253 0.79 GRIK1 (0.55) GRIK1GRIK2TSHRKDM4E
SCHEMBL580204 0.79 GRIK1 (0.55) GRIK1GRIK2TSHRKDM4E
SCHEMBL580203 0.79 GRIK1 (0.55) GRIK1GRIK2TSHRKDM4E
SCHEMBL27831203 0.78 TSHR (0.45) GRIK1GRIK2TSHRKDM4ECPB1
SCHEMBL707103 0.78 TSHR (0.59) GRIK1GRIK2TSHRKDM4ECPB1
SCHEMBL33410 0.78 TSHR (0.59) GRIK1GRIK2TSHRKDM4ECPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090069448-A1 Degradable polymer and process for production thereof JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2009-03-12 US disclosed
EP-1897898-A1 DEGRADABLE POLYMER AND PROCESS FOR PRODUCTION THEREOF Japan Science and Technology Agency (JP) 2008-03-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090069448-A1 Degradable polymer and process for production thereof HPGDS, PPOX, HCCS GRIK1 4458/4885GRIK2 4230/4885TSHR 4225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.