Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA4 | P22748 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414519 | 1.00 | HPGD (0.42) | HPGDMAPK1LMNAOXTRAVPR1A | |
| SCHEMBL4417850 | 0.89 | OXTR (0.51) | HPGDMAPK1LMNAOXTRAVPR1A | |
| SCHEMBL301777 | 0.89 | OXTR (0.51) | HPGDMAPK1LMNAOXTRAVPR1A | |
| SCHEMBL13789901 | 0.88 | SMN1; SMN2 (0.43) | HPGDMAPK1LMNAOXTRAVPR1A | |
| SCHEMBL4422773 | 0.88 | SMN1; SMN2 (0.43) | HPGDMAPK1LMNAOXTRAVPR1A | |
| SCHEMBL8320159 | 0.86 | HPGD (0.44) | HPGDMAPK1LMNAOXTRAVPR1A | |
| SCHEMBL4419397 | 0.86 | HPGD (0.44) | HPGDMAPK1LMNAOXTRAVPR1A | |
| SCHEMBL8338121 | 0.86 | HPGD (0.41) | HPGDMAPK1LMNAOXTRAVPR1A | |
| SCHEMBL4418361 | 0.85 | HPGD (0.43) | HPGDMAPK1LMNAOXTRAVPR1A | |
| SCHEMBL4418365 | 0.85 | HPGD (0.43) | HPGDMAPK1LMNAOXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532109-B1 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | MERCK SERONO SA (CH) | 2009-09-09 | — | — | EP | claimed |