SCHEMBL4414650

SCHEMBL4414650

CC(CC(=O)NN)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.51
LMNA P02545 2/20 0.46
ALDH1A1 P00352 3/20 0.44
HTT P42858 1/20 0.44
TP53 P04637 1/20 0.44
TNF P01375 5/20 0.44
PDE4A P27815 2/20 0.44
PDE4B Q07343 2/20 0.44
PDE4C Q08493 2/20 0.44
PDE4D Q08499 2/20 0.44
POLB P06746 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
KMT2A Q03164 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28569602 0.82 TDP1 (0.59) TDP1LMNAALDH1A1HTTTP53
SCHEMBL8853249 0.80 TDP1 (0.62) TDP1LMNAALDH1A1HTTTP53
SCHEMBL28908606 0.79 TNF (0.60) TDP1LMNAALDH1A1HTTTNF
SCHEMBL9076943 0.79 TDP1 (0.56) TDP1LMNAALDH1A1HTTTP53
SCHEMBL8504158 0.78 TDP1 (0.54) TDP1LMNAALDH1A1HTTTNF
SCHEMBL1757227 0.76 TDP1 (0.53) TDP1LMNAALDH1A1HTTTNF
SCHEMBL11453340 0.76 TNF (0.53) TDP1LMNAALDH1A1HTTTNF
SCHEMBL9174908 0.75 POLB (0.30) HTTPOLB
SCHEMBL7215852 0.75 TDP1 (0.55) TDP1LMNAALDH1A1HTTTP53
SCHEMBL4106122 0.74 TDP1 (0.62) TDP1LMNAALDH1A1HTTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100587001-C Polyacetal resin composition POLYPLASTICS CO 2010-02-03 CN disclosed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
CN-1878834-A Polyacetal resin composition POLYPLASTICS CO (JP) 2006-12-13 CN disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed