Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31051680 | 0.74 | ABCG2 (0.60) | ABCG2ABCB1NPC1RAB9APKM | |
| SCHEMBL12497464 | 0.73 | MAPT (0.43) | NPC1RAB9AHTTMAPTKDM4E | |
| SCHEMBL31051672 | 0.71 | ABCG2 (0.59) | ABCG2ABCB1NPC1RAB9AMAPT | |
| SCHEMBL6751826 | 0.71 | NPC1 (0.61) | ABCG2ABCB1NPC1RAB9AMAPT | |
| SCHEMBL4407260 | 0.71 | RAB9A (0.54) | NPC1RAB9AHTTMAPTSMN1; SMN2 | |
| SCHEMBL6269910 | 0.71 | ABCG2 (0.50) | ABCG2HPGDABCB1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3318213 | 0.70 | NPC1 (0.60) | ABCG2ABCB1NPC1RAB9AMAPT | |
| SCHEMBL28232274 | 0.69 | TSHR (0.37) | NPC1RAB9AHTTMAPTKDM4E | |
| SCHEMBL4410795 | 0.69 | NPC1 (0.55) | ABCG2HPGDABCB1NPC1RAB9A | |
| SCHEMBL28231253 | 0.68 | SMN1; SMN2 (0.49) | HPGDNPC1HTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |