Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751826 | 0.99 | NPC1 (0.61) | NPC1ABCG2SMN1; SMN2PKMRAB9A | |
| SCHEMBL31051680 | 0.93 | ABCG2 (0.60) | NPC1ABCG2SMN1; SMN2PKMRAB9A | |
| Hydrochloric Acid SCHEMBL9098315 | 0.93 | ABCG2 (0.50) | NPC1ABCG2SMN1; SMN2PKMMEN1 | |
| SCHEMBL9660058 | 0.91 | ABCG2 (0.51) | NPC1ABCG2SMN1; SMN2PKMMEN1 | |
| SCHEMBL31051672 | 0.83 | ABCG2 (0.59) | NPC1ABCG2SMN1; SMN2RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL1219233 | 0.81 | NPC1 (0.74) | NPC1ABCG2PKMRAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL8698166 | 0.81 | NPC1 (0.74) | NPC1ABCG2PKMRAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL8698170 | 0.81 | NPC1 (0.74) | NPC1ABCG2PKMRAB9AKDM4E | |
| SCHEMBL29736032 | 0.80 | NPC1 (0.77) | NPC1ABCG2PKMRAB9AL3MBTL1 | |
| SCHEMBL2210517 | 0.79 | NPC1 (0.77) | NPC1ABCG2PKMRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059526-A | Storage stability, accuracy | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1991-10-22 | — | — | US | claimed |
| US-20240418613-A1 | BIOLOGICAL MATERIAL MEASURING INSTRUMENT | TASCOM CO., LTD. (KR) | 2024-12-19 | — | — | US | disclosed |
| US-12078581-B2 | Biological material measuring instrument | TASCOM CO., LTD. (KR) | 2024-09-03 | — | — | US | disclosed |
| US-20230132344-A1 | BIOLOGICAL MATERIAL MEASURING INSTRUMENT | TASCOM CO., LTD. (KR) | 2023-04-27 | — | — | US | disclosed |
| US-20230118308-A1 | BIOMETRIC SYSTEM | TASCOM CO., LTD. (KR) | 2023-04-20 | — | — | US | disclosed |
| US-11561165-B2 | Biometric system | TASCOM CO., LTD. (KR) | 2023-01-24 | — | — | US | disclosed |
| US-11536635-B2 | Biological material, measuring instrument | TASCOM CO., LTD. (KR) | 2022-12-27 | — | — | US | disclosed |
| CN-108700503-B | Biometric identification system | 泰斯科有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-107923838-B | Biological material measuring instrument | 泰斯科有限公司 | 2021-11-26 | — | — | CN | disclosed |
| EP-2803992-B1 | Sample analyzing method by capillary electrophoresis method | ARKRAY INC (JP) | 2021-02-17 | — | — | EP | disclosed |
| EP-0272518-B1 | Analytical element for measuring enzyme activity | FUJI PHOTO FILM CO LTD (JP) | 1994-04-13 | — | — | EP | disclosed |
| EP-0564460-A1 | AN AUGMENTED WESTERN BLOT FORMAT AND IMMUNOASSAY FOR DETECTION OF VIRAL ANTIBODIES | DIAGNOSTIC BIOTECHNOLOGY, INC. (US) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992003579-A1 | AN AUGMENTED WESTERN BLOT FORMAT AND IMMUNOASSAY FOR DETECTION OF VIRAL ANTIBODIES | DIAGNOSTIC BIOTECHNOLOGY, INC. (US) | 1992-03-05 | — | — | WO | disclosed |
| US-5082770-A | Oxidase, dehydrogenase, coenzyme | TOKUYAMA SODA CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| US-5059526-A | Storage stability, accuracy | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1991-10-22 | — | — | US | disclosed |
| US-5006458-A | Accuracy | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0322591-A2 | Antibiotic resistance testing assay | ABBOTT LABORATORIES (US) | 1989-07-05 | — | — | EP | disclosed |
| EP-0272518-A2 | Analytical element for measuring enzyme activity | Fuji Photo Film Co., Ltd. (JP) | 1988-06-29 | — | — | EP | disclosed |
| US-4693971-A | Highly sensitive enzyme assay method | TOYO JOZO KABUSHIKI KAISHA (JP) | 1987-09-15 | — | — | US | disclosed |
| EP-0166505-A2 | Isolation and quantitation of alkaline phosphatase | AKZO N.V. (NL) | 1986-01-02 | — | — | EP | disclosed |