Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1385077 | 0.94 | TPSAB1 (1.00) | TPSAB1 | |
| SCHEMBL15139573 | 0.87 | TPSAB1 (0.76) | TPSAB1 | |
| SCHEMBL15788481 | 0.86 | TPSAB1 (0.75) | TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL4409176 | 0.83 | TPSAB1 (1.00) | TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL4412972 | 0.82 | TPSAB1 (1.00) | TPSAB1 | |
| SCHEMBL6871088 | 0.82 | TPSAB1 (0.70) | TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL4395988 | 0.82 | TPSAB1 (0.79) | TPSAB1 | |
| SCHEMBL15981355 | 0.80 | TPSAB1 (0.66) | TPSAB1 | |
| SCHEMBL27249754 | 0.78 | TPSAB1 (0.62) | TPSAB1 | |
| SCHEMBL13830408 | 0.77 | TPSAB1 (0.62) | TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296972-B1 | ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS | AVENTIS PHARMA INC (US) | 2009-12-23 | — | — | EP | claimed |
| EP-2367812-B1 | [4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-[7-FLUORO-1-(2-METHOXY-ETHYL)-4TRIFLUOROMETHOXY-1H-INDOL-3-YL]METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE | SANOFI SA (FR) | 2015-09-16 | — | — | EP | disclosed |
| EP-2480232-B1 | DISUBSTITUTED ]4-(5-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-1H-INDOL-3-YL]-METHANONES | SANOFI SA (FR) | 2013-10-02 | — | — | EP | disclosed |
| US-8497379-B2 | Method and intermediates for the preparation of 2,2,2-trifluoro-N-(4-fluoro-3-pyridin-4-yl-benzyl)-acetamide hydrochloride | SANOFI (FR) | 2013-07-30 | — | — | US | disclosed |