SCHEMBL15788481

SCHEMBL15788481

Cn1cc(C(=O)N2CCC(c3cccc(CN)c3)CC2)c2ccc([Si](C)(C)O)cc21

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TPSAB1 Q15661 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4414708 0.86 TPSAB1 (1.00) TPSAB1
SCHEMBL15788523 0.84 TPSAB1 (0.57) TPSAB1
SCHEMBL15788478 0.84 TPSAB1 (0.55) TPSAB1
SCHEMBL15788483 0.83 TPSAB1 (0.57) TPSAB1
Trifluoroacetic Acid SCHEMBL1385077 0.82 TPSAB1 (1.00) TPSAB1
SCHEMBL18652733 0.82 TPSAB1 (0.68) TPSAB1
SCHEMBL15788520 0.81 TPSAB1 (0.55) TPSAB1
SCHEMBL14885441 0.81 TPSAB1 (0.56) TPSAB1
SCHEMBL18652696 0.80 TPSAB1 (0.72) TPSAB1
SCHEMBL15788526 0.80 TPSAB1 (0.54) TPSAB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10912786-B2 Silyl monomers capable of multimerizing in an aqueous solution, and methods of using same CORNELL UNIVERSITY (US) 2021-02-09 US disclosed
US-20170080001-A1 SILYL MONOMERS CAPABLE OF MULTIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME CORNELL UNIVERSITY 2017-03-23 US disclosed
US-20170080001-A1 SILYL MONOMERS CAPABLE OF MULTIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME CORNELL UNIVERSITY 2017-03-23 US disclosed
US-20140163229-A1 SILYL MONOMERS CAPABLE OF MULTIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME CORNELL UNIVERSITY (US) 2014-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10912786-B2 Silyl monomers capable of multimerizing in an aqueous solution, and methods of using same STIM1, STAMBP, ILK TPSAB1 2594/4885
US-20170080001-A1 SILYL MONOMERS CAPABLE OF MULTIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME STIM1, STAMBP, ILK TPSAB1 2594/4885
US-20140163229-A1 SILYL MONOMERS CAPABLE OF MULTIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME STIM1, STAMBP, ILK TPSAB1 2594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.