SCHEMBL4414715

SCHEMBL4414715

NNC(=O)CCN1C(=O)CCC1=O

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.48
KMT2A Q03164 3/20 0.45
HTT P42858 2/20 0.43
POLB P06746 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 1/20 0.42
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 2/20 0.40
CTSD P07339 1/20 0.40
KDM5C P41229 1/20 0.40
PHF8 Q9UPP1 1/20 0.40
KDM2A Q9Y2K7 1/20 0.40
LMNA P02545 1/20 0.39
ALPL P05186 1/20 0.38
MEN1 O00255 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ALOX12 P18054 1/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4419329 0.92 MAPT (0.50) MAPTKMT2AHTTPOLBSMN1; SMN2
SCHEMBL6991622 0.85 SMN1; SMN2 (0.58) MAPTKMT2AHTTPOLBSMN1; SMN2
SCHEMBL4408742 0.82 MAPT (0.47) MAPTKMT2AHTTPOLBALDH1A1
SCHEMBL13056596 0.82 HTT (0.52) MAPTKMT2AHTTPOLBSMN1; SMN2
SCHEMBL14030157 0.81 HTT (0.51) MAPTKMT2AHTTPOLBSMN1; SMN2
SCHEMBL24259802 0.80 SMN1; SMN2 (0.42) MAPTKMT2AHTTPOLBSMN1; SMN2
SCHEMBL14227570 0.80 SMN1; SMN2 (0.45) MAPTKMT2AHTTPOLBSMN1; SMN2
SCHEMBL13268072 0.78 SMN1; SMN2 (0.55) MAPTKMT2AHTTPOLBSMN1; SMN2
SCHEMBL14930710 0.78 SMN1; SMN2 (0.51) MAPTKMT2AHTTPOLBSMN1; SMN2
SCHEMBL21119414 0.77 SMN1; SMN2 (0.50) MAPTKMT2AHTTPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873281-B2 Conjugates of cell binding molecules with cytotoxic agents HANGZHOU DAC BIOTECH CO., LTD. (CN) 2024-01-16 US disclosed
US-20200172480-A1 CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2020-06-04 US disclosed
US-8895965-B2 Photoelectric conversion element, production method for a photoelectric conversion element, solid-state image sensor, production method for a solid-state image sensor, electronic apparatus, photoconductor, production method for a photoconductor and multilayer transparent photoelectric conversion element SONY CORPORATION (JP) 2014-11-25 US disclosed
US-8895965-B2 Photoelectric conversion element, production method for a photoelectric conversion element, solid-state image sensor, production method for a solid-state image sensor, electronic apparatus, photoconductor, production method for a photoconductor and multilayer transparent photoelectric conversion element SONY CORPORATION (JP) 2014-11-25 US disclosed
US-8884899-B2 Three-dimensional interactive display SONY CORPORATION (JP) 2014-11-11 US disclosed
US-8884899-B2 Three-dimensional interactive display SONY CORPORATION (JP) 2014-11-11 US disclosed
US-20120228587-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD FOR A PHOTOELECTRIC CONVERSION ELEMENT, SOLID-STATE IMAGE SENSOR, PRODUCTION METHOD FOR A SOLID-STATE IMAGE SENSOR, ELECTRONIC APPARATUS, PHOTOCONDUCTOR, PRODUCTION METHOD FOR A PHOTOCONDUCTOR AND MULTILAYER TRANSPARENT PHOTOELECTRIC CONVERSION ELEMENT SONY CORPORATION (JP) 2012-09-13 US disclosed
US-20120228587-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD FOR A PHOTOELECTRIC CONVERSION ELEMENT, SOLID-STATE IMAGE SENSOR, PRODUCTION METHOD FOR A SOLID-STATE IMAGE SENSOR, ELECTRONIC APPARATUS, PHOTOCONDUCTOR, PRODUCTION METHOD FOR A PHOTOCONDUCTOR AND MULTILAYER TRANSPARENT PHOTOELECTRIC CONVERSION ELEMENT SONY CORPORATION (JP) 2012-09-13 US disclosed
CN-100587001-C Polyacetal resin composition POLYPLASTICS CO 2010-02-03 CN disclosed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
CN-1878834-A Polyacetal resin composition POLYPLASTICS CO (JP) 2006-12-13 CN disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11873281-B2 Conjugates of cell binding molecules with cytotoxic agents CD4, CD2, CD47 MAPT 4147/4885KMT2A 2615/4885HTT 3236/4885
US-20200172480-A1 CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS CD4, CD2, CD47 MAPT 4147/4885KMT2A 2615/4885HTT 3236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.