Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414715 | 0.80 | MAPT (0.48) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL14227570 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL21119414 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL18943850 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL14934677 | 0.76 | HTT (0.52) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL29229819 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL14930710 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL18471568 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL13268072 | 0.74 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL57076 | 0.74 | ALDH1A1 (0.54) | SMN1; SMN2HPGDHTTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3432934-B1 | PRODRUGS OF CYTOTOXIC AGENTS WITH ENZYMATICALLY CLEAVABLE GROUPS | Bayer Pharma AG (DE) | 2022-02-23 | — | — | EP | disclosed |