SCHEMBL4419329

SCHEMBL4419329

NNC(=O)CCN1C(=O)CCCC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
KMT2A Q03164 3/20 0.43
POLB P06746 3/20 0.41
HTT P42858 2/20 0.41
MEN1 O00255 2/20 0.40
KDM4E B2RXH2 2/20 0.38
CTSD P07339 1/20 0.38
KDM5C P41229 1/20 0.38
PHF8 Q9UPP1 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 2/20 0.37
HPGD P15428 1/20 0.37
ALDH1A1 P00352 2/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
TSHR P16473 2/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4414715 0.92 MAPT (0.48) MAPTKMT2APOLBHTTMEN1
SCHEMBL4408742 0.79 MAPT (0.47) MAPTKMT2APOLBHTTMEN1
SCHEMBL6991622 0.79 SMN1; SMN2 (0.58) MAPTKMT2APOLBHTTMEN1
SCHEMBL5200032 0.76 ALDH1A1 (0.50) KMT2APOLBMEN1KDM4ELMNA
SCHEMBL13056596 0.76 HTT (0.52) MAPTKMT2APOLBHTTMEN1
SCHEMBL14030157 0.75 HTT (0.51) MAPTKMT2APOLBHTTMEN1
SCHEMBL26092142 0.75 KMT2A (0.47) MAPTKMT2APOLBHTTMEN1
SCHEMBL27660379 0.74 MAPT (0.44) MAPTKMT2APOLBHTTMEN1
SCHEMBL30515509 0.74 MAPT (0.42) MAPTKMT2APOLBHTTMEN1
SCHEMBL24259802 0.73 SMN1; SMN2 (0.42) MAPTKMT2APOLBHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100587001-C Polyacetal resin composition POLYPLASTICS CO 2010-02-03 CN disclosed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
CN-1878834-A Polyacetal resin composition POLYPLASTICS CO (JP) 2006-12-13 CN disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed