SCHEMBL4414865

SCHEMBL4414865

O=[PH](Oc1ccc(Br)c(Br)c1)Oc1ccc(Br)c(Br)c1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
HSP90AA1 P07900 1/20 0.33
TLR9 Q9NR96 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11039400 0.81 NR4A1 (0.35) NPC1MAPTRAB9AHSP90AA1TLR9
SCHEMBL3363883 0.73 CA1 (0.43) MAPTRAB9A
SCHEMBL14938867 0.72 NR4A1 (0.42) NPC1MAPTRAB9A
SCHEMBL29492090 0.72 NR4A1 (0.42) NPC1MAPTRAB9A
SCHEMBL3361603 0.71 SOD1 (0.49) MAPTRAB9A
SCHEMBL1134723 0.70 CA1 (0.53) NPC1MAPTRAB9A
SCHEMBL30250475 0.70 CA1 (0.53) NPC1MAPTRAB9A
SCHEMBL4406231 0.70 CA2 (0.61) NPC1MAPTRAB9A
SCHEMBL233807 0.69 CA1 (0.58) NPC1MAPTRAB9A
SCHEMBL4800898 0.69 NPC1 (0.33) NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7635748-B2 Resin and article molded therefrom TORAY INDUSTRIES, INC. (JP) 2009-12-22 US disclosed
EP-1270646-B1 RESIN COMPOSITION AND ARTICLES MOLDED THEREFROM TORAY INDUSTRIES (JP) 2008-11-26 EP disclosed
US-20080139778-A1 Resin and article molded therefrom TAKANISHI KEIJIRO 2008-06-12 US disclosed
US-20060287464-A1 Resin and article molded therefrom TORAY INDUSTRIES, INC. (JP) 2006-12-21 US disclosed
EP-1640405-A1 RESIN AND ARTICLE MOLDED THEREFROM TORAY INDUSTRIES, INC. (JP) 2006-03-29 EP disclosed
US-6750313-B2 HIGH REFRACTIVE INDEX AND LOW DISPERSION CHARACTERISTICS; OPTICAL LENSES, FILMS, DISCS; POLYCARBONATE RESIN CONTAINING A PHOSPHONIC ACID GROUP TORAY INDUSTRIES, INC. (JP) 2004-06-15 US disclosed
US-20030013836-A1 Resin composition and articles molded therefrom TORAY INDUSTRIES, INC., A CORPORATION OF JAPAN (JP) 2003-01-16 US disclosed
EP-1270646-A1 RESIN COMPOSITION AND ARTICLES MOLDED THEREFROM TORAY INDUSTRIES, INC. (JP) 2003-01-02 EP disclosed