Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415340 | 1.00 | MIF (0.67) | MIFCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14926713 | 0.86 | NFE2L2 (0.49) | MIFNFE2L2CYP1A1CYP1B1KLKB1 | |
| SCHEMBL5199344 | 0.86 | MIF (0.53) | MIFCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5199333 | 0.86 | MIF (0.53) | MIFCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25733407 | 0.84 | NFE2L2 (0.47) | MIFNFE2L2HDAC3HDAC4HDAC1 | |
| SCHEMBL26316886 | 0.84 | NFE2L2 (0.47) | MIFNFE2L2CYP1A1CYP1B1KLKB1 | |
| SCHEMBL584565 | 0.81 | CYP1A1 (0.55) | MIFCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30278658 | 0.81 | CYP1A1 (0.55) | MIFCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL584566 | 0.81 | CYP1A1 (0.55) | MIFCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29407005 | 0.81 | MIF (0.71) | MIFCYP2C19NFE2L2TDO2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096109-A1 | CARBOXYLIC ACID DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |