Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 15/20 | 0.60 |
| ▸ | GSTA1 | P08263 | 9/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.60 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.60 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.60 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.60 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408419 | 0.86 | GSTP1 (0.60) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL4407253 | 0.83 | GSTP1 (0.63) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL4411487 | 0.80 | GSTP1 (0.64) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL21062153 | 0.80 | GSTP1 (0.70) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL21062152 | 0.80 | GSTP1 (0.70) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL8907142 | 0.79 | GSTP1 (0.66) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL25070638 | 0.79 | GSTP1 (0.65) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL7214285 | 0.79 | GSTP1 (0.76) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL7214202 | 0.78 | GSTP1 (0.74) | GSTP1GSTA1MEN1ALDH1A1KMT2A | |
| SCHEMBL22486549 | 0.78 | GSTP1 (0.67) | GSTP1GSTA1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060135609-A1 | Ophthamological drugs | DUKE UNIVERSITY (US) | 2006-06-22 | — | — | US | claimed |
| US-10485550-B2 | Ophthalmic drug delivery device and methods of use | DUKE UNIVERSITY (US) | 2019-11-26 | — | — | US | disclosed |
| US-20150057689-A1 | OPHTHALMIC DRUG DELIVERY DEVICE AND METHODS OF USE | DUKE UNIVERSITY (US) | 2015-02-26 | — | — | US | disclosed |
| US-8642644-B2 | Ophthamological drugs | DUKE UNIVERSITY (US) | 2014-02-04 | — | — | US | disclosed |
| US-20090318542-A1 | OPHTHAMOLOGICAL DRUGS | DUKE UNIVERSITY | 2009-12-24 | — | — | US | disclosed |
| US-20060135609-A1 | Ophthamological drugs | DUKE UNIVERSITY (US) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135609-A1 | Ophthamological drugs | QDPR, PTGIR, PDE6C | GSTP1 819/4885GSTA1 1309/4885MEN1 1946/4885 |
| US-20090318542-A1 | OPHTHAMOLOGICAL DRUGS | QDPR, PTGIR, PDE6C | GSTP1 939/4885GSTA1 1449/4885MEN1 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.