SCHEMBL7214285

SCHEMBL7214285

C=C(CC)C(=O)c1ccc(OCC(=O)OC)c(Cl)c1Cl

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 15/20 0.76
GSTA1 P08263 9/20 0.76
LMNA P02545 2/20 0.76
MEN1 O00255 1/20 0.76
ABCC3 O15438 1/20 0.76
PLIN1 O60240 1/20 0.76
ALDH1A1 P00352 1/20 0.76
TP53 P04637 1/20 0.76
MAPT P10636 1/20 0.76
HSPD1 P10809 1/20 0.76
CYP2C9 P11712 1/20 0.76
TSHR P16473 1/20 0.76
HTT P42858 1/20 0.76
RECQL P46063 1/20 0.76
MAP2K6 P52564 1/20 0.76
HSPE1 P61604 1/20 0.76
GSTO1 P78417 1/20 0.76
PLIN5 Q00G26 1/20 0.76
KMT2A Q03164 1/20 0.76
ATM Q13315 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1525419 0.89 GSTP1 (0.65) GSTP1GSTA1LMNAMEN1ABCC3
SCHEMBL7214202 0.88 GSTP1 (0.74) GSTP1GSTA1LMNAMEN1ABCC3
SCHEMBL3713736 0.86 GSTP1 (0.80) GSTP1GSTA1LMNAMEN1ABCC3
SCHEMBL10031684 0.86 GSTP1 (0.80) GSTP1GSTA1LMNAMEN1ABCC3
Ethacrynic Acid SCHEMBL26353 0.86 GSTP1 (1.00) GSTP1GSTA1LMNAMEN1ABCC3
Ethacrynic Acid SCHEMBL29384243 0.86 GSTP1 (1.00) GSTP1GSTA1LMNAMEN1ABCC3
SCHEMBL10014667 0.86 GSTP1 (0.80) GSTP1GSTA1LMNAMEN1ABCC3
Ethacrynic Acid SCHEMBL9108011 0.86 GSTP1 (1.00) GSTP1GSTA1LMNAMEN1ABCC3
SCHEMBL22260541 0.86 GSTP1 (0.71) GSTP1GSTA1LMNAMEN1ABCC3
SCHEMBL16502233 0.86 GSTP1 (0.74) GSTP1GSTA1LMNAMEN1ABCC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4100448-A1 HIGH TG ACRYLATE COPOLYMERS WITH NITROGEN-CONTAINING AROMATIC HETEROCYCLIC GROUP tesa SE (DE) 2022-12-14 EP claimed
US-20110077430-A1 Method and precursor for production of no-carrier-added N-(4-[18F] fluorobutyl)-Ethacrynic amide INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) 2011-03-31 US disclosed
US-20110077430-A1 Method and precursor for production of no-carrier-added N-(4-[18F] fluorobutyl)-Ethacrynic amide INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) 2011-03-31 US disclosed
EP-0688798-B2 MALEIMIDE COPOLYMER AND RESIN COMPOSITION CONTAINING THE SAME MITSUBISHI RAYON CO (JP) 2003-08-27 EP disclosed
US-5948879-A TERPOLYMER OF A MALEIMIDE, VINYLAROMATIC AND ANOTHER MONOMER;MELT PROCESSABILITY; INTRINSIC VISCOSITY OF FROM 0.3 TO 1.5.; YELLOW INDEX OF 30 OR LESS. MITSUBISHI RAYON CO., LTD. (JP) 1999-09-07 US disclosed
EP-0688798-B1 MALEIMIDE COPOLYMER AND RESIN COMPOSITION CONTAINING THE SAME MITSUBISHI RAYON CO (JP) 1999-08-18 EP disclosed
EP-0688798-A1 MALEIMIDE COPOLYMER AND RESIN COMPOSITION CONTAINING THE SAME MITSUBISHI RAYON CO., LTD. (JP) 1995-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110077430-A1 Method and precursor for production of no-carrier-added N-(4-[18F] fluorobutyl)-Ethacrynic amide PFAS, NAPA, NAA15 GSTP1 233/4885GSTA1 66/4885LMNA 679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.