SCHEMBL4415380

SCHEMBL4415380

[CH2]SC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4425339 0.97 LMNA (0.33) LMNA
SCHEMBL4415815 0.87
SCHEMBL1978019 0.73 LMNA (0.42) LMNATHRB
SCHEMBL8105478 0.73 LMNA (0.42) LMNATHRB
SCHEMBL8166292 0.72
SCHEMBL3833946 0.71 LMNA (0.40) LMNATHRB
SCHEMBL984715 0.71 LMNA (0.61) LMNATHRB
Perflexane SCHEMBL3671912 0.71 LMNA (0.61) LMNATHRB
SCHEMBL1924377 0.71 LMNA (0.61) LMNATHRB
Perflexane SCHEMBL7507426 0.71 LMNA (0.61) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1392779-B1 FLUORINATED-PHOTOINITIATORS IN DUAL CURE RESINS CIBA HOLDING INC (CH) 2009-04-22 EP disclosed
US-20040067311-A1 Fluorinated-photoinitiators in dual cure resins CIBA SPECIALTY CHEMICALS CORP. 2004-04-08 US disclosed
EP-1392779-A1 FLUORINATED-PHOTOINITIATORS IN DUAL CURE RESINS Ciba SC Holding AG (CH) 2004-03-03 EP disclosed
WO-2002040602-A1 FLUORINATED-PHOTOINITIATORS IN DUAL CURE RESINS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-05-23 WO disclosed