Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Ciaftalan. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ciaftalan SCHEMBL6037601 | 1.00 | MEN1 (0.45) | MEN1KMT2ATDP1RECQLTHRB | |
| Ciaftalan SCHEMBL4970464 | 1.00 | MEN1 (0.45) | MEN1KMT2ATDP1RECQLTHRB | |
| Ciaftalan SCHEMBL14690839 | 1.00 | MEN1 (0.45) | MEN1KMT2ATDP1RECQLTHRB | |
| Ciaftalan SCHEMBL8909497 | 0.98 | MEN1 (0.44) | MEN1KMT2ATDP1RECQLTHRB | |
| Ciaftalan SCHEMBL6037014 | 0.98 | MEN1 (0.44) | MEN1KMT2ATDP1RECQLTHRB | |
| Ciaftalan SCHEMBL8909846 | 0.98 | MEN1 (0.44) | MEN1KMT2ATDP1RECQLTHRB | |
| Ciaftalan SCHEMBL29356273 | 0.98 | MEN1 (0.46) | MEN1KMT2ATDP1RECQLTHRB | |
| SCHEMBL813083 | 0.98 | MEN1 (0.46) | MEN1KMT2ATDP1RECQLTHRB | |
| Ciaftalan SCHEMBL29360952 | 0.98 | MEN1 (0.46) | MEN1KMT2ATDP1RECQLTHRB | |
| Ciaftalan SCHEMBL1728179 | 0.98 | MEN1 (0.46) | MEN1KMT2ATDP1RECQLTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520894-A | Method of tracking a source display panel of an electronic device that captures an illegal copy of an image by a camera and electronic device for tracking an illegal copy of an image captured by a camera from a source display panel of an electronic device | BOE TECHNOLOGY GROUP CO LTD | 2019-11-29 | — | — | CN | disclosed |
| US-8242262-B2 | Process for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA'DI ESERCIZIO S.P.A. (IT) | 2012-08-14 | — | — | US | disclosed |
| CN-101193893-B | Process for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA'DI ESERCIZIO S.P.A. (IT) | 2011-12-14 | — | — | CN | disclosed |
| EP-1883640-B1 | PROCESS FOR PREPARING CHLORIDES OF PHTHALOCYANINE DERIVATIVES COMPRISING AT LEAST A QUATERNARY AMMONIUM GROUP | MOLTENI & C (IT) | 2009-08-26 | — | — | EP | disclosed |
| US-20090131393-A1 | Process for Preparing Chlorides of Phthalocyanine Derivatives Comprising at Least a Quaternary Ammonium Group | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO S.P.A. (IT) | 2009-05-21 | — | — | US | disclosed |
| CN-101193893-A | Process for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group | MOLTENI & C (IT) | 2008-06-04 | — | — | CN | disclosed |
| EP-1883640-A2 | PROCESS FOR PREPARING CHLORIDES OF PHTHALOCYANINE DERIVATIVES COMPRISING AT LEAST A QUATERNARY AMMONIUM GROUP | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO SOCIETA' PER AZIONI (IT) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006117396-A2 | PROCESS FOR PREPARING CHLORIDES OF PHTHALOCYANINE DERIVATIVES COMPRISING AT LEAST A QUATERNARY AMMONIUM GROUP | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO S.P.A. (IT) | 2006-11-09 | — | — | WO | disclosed |
| US-5656751-A | COMPLEX OF PHTHALOCYANINE, A PHTHALOCYANINE DERIVATIVE, A PHTHALOCYANINE WITH CENTRAL METAL OR NONMETAL AND IODINE; EXCELLENT HEAT AND WEATHER RESISTANCE | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 1997-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131393-A1 | Process for Preparing Chlorides of Phthalocyanine Derivatives Comprising at Least a Quaternary Ammonium Group | PHLPP1, PHPT1, PHLPP2 | MEN1 754/4885KMT2A 673/4885TDP1 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.