SCHEMBL4415826

SCHEMBL4415826

COc1cc(C=Cc2ccc(N(c3ccccc3)c3cccc(C)c3)cc2)c(OC)cc1C=Cc1ccc(N(c2ccccc2)c2cccc(C)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 6/20 0.46
CYP1B1 Q16678 6/20 0.46
CYP1A2 P05177 5/20 0.46
NFE2L2 Q16236 4/20 0.45
RELA Q04206 1/20 0.44
TRPA1 O75762 1/20 0.44
SLC16A3 O15427 1/20 0.44
SLC16A1 P53985 1/20 0.44
APP P05067 2/20 0.41
TUBB1 Q9H4B7 3/20 0.40
MAPT P10636 2/20 0.40
NQO2 P16083 1/20 0.40
CYP19A1 P11511 1/20 0.40
TUBB4A P04350 2/20 0.40
TUBB P07437 2/20 0.40
TUBA3C P0DPH7 2/20 0.40
TUBA1B P68363 2/20 0.40
TUBA4A P68366 2/20 0.40
TUBB4B P68371 2/20 0.40
TUBB3 Q13509 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9915628 1.00 CYP1A1 (0.46) CYP1A1CYP1B1CYP1A2NFE2L2RELA
SCHEMBL13479742 0.91 NFE2L2 (0.51) CYP1A1CYP1B1CYP1A2NFE2L2RELA
SCHEMBL12533834 0.91 NFE2L2 (0.51) CYP1A1CYP1B1CYP1A2NFE2L2RELA
SCHEMBL12382120 0.90 CYP1A1 (0.54) CYP1A1CYP1B1CYP1A2NFE2L2RELA
SCHEMBL3818688 0.90 CYP1A1 (0.54) CYP1A1CYP1B1CYP1A2NFE2L2RELA
SCHEMBL14769035 0.86 CYP1A1 (0.48) CYP1A1CYP1B1CYP1A2NFE2L2TRPA1
SCHEMBL7716044 0.86 RELA (0.48) CYP1A2NFE2L2RELAAPPMAPT
SCHEMBL7717148 0.86 RELA (0.48) CYP1A2NFE2L2RELAAPPMAPT
SCHEMBL13372121 0.86 RELA (0.48) CYP1A2NFE2L2RELAAPPMAPT
SCHEMBL10128949 0.86 RELA (0.48) CYP1A2NFE2L2RELAAPPMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090323747-A1 ORGANIC SOLID-STATE DYE LASER JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2009-12-31 US disclosed