Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20233633 | 0.88 | NR1H2 (0.51) | NR1H2NAMPTRORCUSP2SMN1; SMN2 | |
| SCHEMBL7288803 | 0.86 | MEN1 (0.49) | NR1H2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL25308738 | 0.85 | KDM4E (0.50) | NR1H2USP2SMN1; SMN2KDM4EPKM | |
| SCHEMBL23585483 | 0.84 | NR1H2 (0.54) | NR1H2NAMPTRORCUSP2SMN1; SMN2 | |
| SCHEMBL26089813 | 0.82 | NR1H2 (0.47) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E | |
| SCHEMBL26092681 | 0.81 | NR1H2 (0.55) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E | |
| SCHEMBL894282 | 0.80 | NR1H2 (0.57) | NR1H2NAMPTRORCUSP2SMN1; SMN2 | |
| SCHEMBL20111214 | 0.80 | NR1H2 (0.57) | NR1H2NAMPTRORCUSP2SMN1; SMN2 | |
| SCHEMBL71546 | 0.80 | NR1H2 (0.57) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E | |
| SCHEMBL20572907 | 0.80 | NR1H2 (0.50) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325924-A1 | GPCR Agonists | PROSIDION LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
| US-20090325924-A1 | GPCR Agonists | PROSIDION LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
| US-20090325924-A1 | GPCR Agonists | PROSIDION LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
| WO-2007003960-A1 | GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325924-A1 | GPCR Agonists | GPR119, GCGR, GPR27 | NR1H2 70/4885NAMPT 2587/4885RORC 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.