SCHEMBL4415925

SCHEMBL4415925

CC1(OC(=O)N2CCC(OCc3nc(-c4ccc(S(C)(=O)=O)c(Cl)c4)no3)CC2)CCC1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 10/20 0.53
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
HTT P42858 1/20 0.37
KCNH2 Q12809 1/20 0.37
LMNA P02545 2/20 0.36
CNR1 P21554 2/20 0.36
CNR2 P34972 2/20 0.36
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HPGD P15428 1/20 0.34
SCN9A Q15858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4414293 0.88 GPR119 (0.68) GPR119
SCHEMBL4426169 0.87 GPR119 (0.57) GPR119CYP2C9CYP2C19SMN1; SMN2KCNH2
SCHEMBL4414300 0.87 GPR119 (0.52) GPR119CYP2C9CYP2C19SMN1; SMN2CYP1A2
SCHEMBL4415731 0.82 GPR119 (0.57) GPR119CYP2C9CYP2C19SMN1; SMN2CYP1A2
SCHEMBL4415985 0.80 GPR119 (0.52) GPR119CYP2C9CYP2C19KCNH2
SCHEMBL4422138 0.79 GPR119 (0.69) GPR119
SCHEMBL4415786 0.79 GPR119 (0.68) GPR119
SCHEMBL4415852 0.79 GPR119 (0.70) GPR119
SCHEMBL14640819 0.78 GPR119 (0.54) GPR119SMN1; SMN2HTTLMNACNR1
SCHEMBL4413067 0.78 GPR119 (0.67) GPR119SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090325924-A1 GPCR Agonists PROSIDION LIMITED (GB) 2009-12-31 US disclosed
US-20090325924-A1 GPCR Agonists PROSIDION LIMITED (GB) 2009-12-31 US disclosed
US-20090325924-A1 GPCR Agonists PROSIDION LIMITED (GB) 2009-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090325924-A1 GPCR Agonists GPR119, GCGR, GPR27 GPR119 1/4885CYP2C9 1662/4885CYP2C19 1165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.