Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193008 | 0.71 | CYP2A6 (0.50) | CYP2A6HSD17B1HSD17B2ALDH1A1MEN1 | |
| SCHEMBL144429 | 0.64 | CYP2A6 (0.45) | CYP2A6HSD17B1HSD17B2ALDH1A1MEN1 | |
| SCHEMBL4463309 | 0.63 | CYP2A6 (0.33) | CYP2A6HSD17B1HSD17B2 | |
| SCHEMBL15287265 | 0.62 | CYP2A6 (0.36) | CYP2A6HSD17B1HSD17B2ALDH1A1MEN1 | |
| SCHEMBL21777333 | 0.61 | HSD17B1 (0.43) | CYP2A6HSD17B1HSD17B2KDM4EPDGFRB | |
| SCHEMBL679889 | 0.61 | ALDH1A1 (0.40) | CYP2A6HSD17B1HSD17B2ALDH1A1MEN1 | |
| SCHEMBL1638687 | 0.60 | CYP2A6 (0.38) | CYP2A6HSD17B1HSD17B2ALDH1A1MEN1 | |
| SCHEMBL5536652 | 0.60 | CYP2A6 (0.37) | CYP2A6HSD17B1HSD17B2ALDH1A1MEN1 | |
| SCHEMBL19677275 | 0.60 | KDM4E (0.40) | CYP2A6HSD17B1HSD17B2ALDH1A1MEN1 | |
| SCHEMBL5727958 | 0.60 | HSD17B1 (0.38) | CYP2A6HSD17B1HSD17B2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592387-A4 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARM INC (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-1592387-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | Elan Pharmaceuticals, Inc. (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004066932-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARMACEUTICALS INC. (US) | 2004-08-12 | — | — | WO | disclosed |