Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4416195 | 1.00 | MDM4 (0.42) | MDM4TP53CASP3KMT2ASLC17A5 | |
| SCHEMBL4406592 | 0.85 | KIF11 (0.39) | MDM4TP53KMT2A | |
| SCHEMBL10312386 | 0.81 | CASP3 (0.48) | MDM4TP53CASP3KMT2A | |
| SCHEMBL12510929 | 0.81 | CASP3 (0.48) | MDM4TP53CASP3KMT2A | |
| SCHEMBL4406195 | 0.81 | MDM4 (0.39) | MDM4TP53KMT2A | |
| SCHEMBL5998507 | 0.79 | MDM4 (0.55) | MDM4TP53CASP3KMT2ASLC17A5 | |
| SCHEMBL1738641 | 0.79 | MDM4 (0.55) | MDM4TP53CASP3KMT2ASLC17A5 | |
| SCHEMBL29395463 | 0.79 | MDM4 (0.55) | MDM4TP53CASP3KMT2ASLC17A5 | |
| SCHEMBL29503847 | 0.79 | MDM4 (0.55) | MDM4TP53CASP3KMT2ASLC17A5 | |
| SCHEMBL29560536 | 0.79 | MDM4 (0.55) | MDM4TP53CASP3KMT2ASLC17A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085403-A1 | PROCESS FOR PRODUCTION OF PEPTIDE THIOESTER | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2009-08-05 | — | — | EP | disclosed |